ArticleBiopolymers2013
Story in a sample-the potential (and limitations) of cryo-electron microscopy applied to molecular machines.
Article in Biopolymers, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Insights into protein structure using cryogenic light microscopy.Biochemical Society transactions · 2023Review
- Construction of Histone-Protein Complex Structures by Peptide Growing.International journal of molecular sciences · 2023Article
- Microscopic Techniques for the Analysis of Micro and Nanostructures of Biopolymers and Their Derivatives.Polymers · 2020Review
- Evolution of a dynamic molecular switch.IUBMB life · 2019Review
- Continuous changes in structure mapped by manifold embedding of single-particle data in cryo-EM.Methods (San Diego, Calif.) · 2016Article
- Ion Mobility Spectrometry-Hydrogen Deuterium Exchange Mass Spectrometry of Anions: Part 3. Estimating Surface Area Exposure by Deuterium Uptake.Journal of the American Society for Mass Spectrometry · 2016Article
- Two promising future developments of cryo-EM: capturing short-lived states and mapping a continuum of states of a macromolecule.Microscopy (Oxford, England) · 2016Review
- Quantitative Connection between Ensemble Thermodynamics and Single-Molecule Kinetics: A Case Study Using Cryogenic Electron Microscopy and Single-Molecule Fluorescence Resonance Energy Transfer Investigations of the Ribosome.The journal of physical chemistry. B · 2015Article
- Article
- Covariance Matrix Estimation for the Cryo-EM Heterogeneity Problem.SIAM journal on imaging sciences · 2015Article
- CENP-A arrays are more condensed than canonical arrays at low ionic strength.Biophysical journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This article addresses recent developments in cryo-electron microscopy and single-particle reconstruction of macromolecules. With the advent of powerful classification techniques, it is now possible to extract and visualize multiple conformers contained within the same dataset. It is discussed how and to what extent this technique can be used in the study of the dynamics of molecular machines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.