Trial reportThe British journal of surgery2013
Health-related quality of life after laparoscopic and open surgery for rectal cancer in a randomized trial.
Trial report in The British journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT00297791 (A Randomized Clinical Trial Comparing Laparoscopic and Open Surgery for Rectal Cancer.), which is not on this map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Clinical Trial Comparing Laparoscopic and Open Surgery for Rectal Cancer.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Intraoperative neuromonitoring in rectal cancer surgery: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Functional complaints and quality of life after transanal total mesorectal excision: a meta-analysis.The British journal of surgery · 2020Pooled it
- Developing a multivariable prediction model of global health-related quality of life in patients treated for rectal cancer: a prospective study in five countries.International journal of colorectal disease · 2024Trial
- Quality of life in a randomized trial of early closure of temporary ileostomy after rectal resection for cancer (EASY trial).The British journal of surgery · 2018Trial
- Patient-reported genitourinary dysfunction after laparoscopic and open rectal cancer surgery in a randomized trial (COLOR II).The British journal of surgery · 2014Trial
- A randomized clinical trial of nerve block to manage end-stage pancreatic cancerous pain.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Trial
- Open sphincter-preserving surgery of extraperitoneal rectal cancer without primary stoma and Fast Track Protocol.Il Giornale di chirurgiaTrial
- Postoperative Morbidity Is Not Associated with a Worse Mid-Term Quality of Life After Colorectal Surgery for Colorectal Carcinoma.Journal of clinical medicine · 2025Article
- Quality of Life in Rectal Cancer Treatments: An Updated Systematic Review of Randomized Controlled Trials (2013-2023).Cancers · 2025Review
- The Potential Health Economic Value of Adding Magnetomotive Ultrasound to Current Diagnostic Methods for Detecting Lymph Node Metastases in Rectal Cancer.PharmacoEconomics · 2025Article
- Does transanal total mesorectal excision (taTME) result in better quality of life and functional outcomes than traditional TME does? A retrospective propensity score-adjusted cohort study.Langenbeck's archives of surgery · 2025Observational
- Article
- Functional Outcomes of Emergency Surgery for Perforated Diverticulitis, Hinchey Grade III.World journal of surgery · 2023Observational
- Outcomes of open vs laparoscopic vs robotic vs transanal total mesorectal excision (TME) for rectal cancer: a network meta-analysis.Techniques in coloproctology · 2023Review
- Medium-term surgical outcomes and health-related quality of life after laparoscopicWorld journal of gastrointestinal endoscopy · 2023Article
- Observational
- Construct validity and responsiveness of the Duke Activity Status Index (DASI) as a measure of recovery after colorectal surgery.Surgical endoscopy · 2022Article
- The Quality of Life of Patients with Surgically Treated Colorectal Cancer: A Narrative Review.Journal of clinical medicine · 2022Review
- Multimodal Treatment of Rectal Cancer.Deutsches Arzteblatt international · 2022Review
- Predictors of Quality of Life Six Years after Curative Colorectal Cancer Surgery: Results of the Prospective Multicenter Study.Medicina (Kaunas, Lithuania) · 2022Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies comparing laparoscopic and open surgical techniques have reported improved health-related quality of life (HRQL). This analysis compared HRQL 12 months after laparoscopic versus open surgery for rectal cancer in a subset of a randomized trial.
methodsThe setting was a multicentre randomized trial (COLOR II) comparing laparoscopic and open surgery for rectal cancer. Involvement in the HRQL study of COLOR II was optional. Patients completed the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-CR38, and EuroQol - 5D (EQ-5D™) before surgery, and 4 weeks, 6, 12 and 24 months after operation. Analysis was done according to the manual for each instrument.
resultsOf 617 patients in hospitals participating in the HRQL study of COLOR II, 385 were included. The HRQL deteriorated to moderate/severe degrees after surgery, gradually returning to preoperative values over time. Changes in EORTC QLQ-C30 and QLQ-CR38, and EQ-5D™ were not significantly different between the groups regarding global health score or any of the dimensions or symptoms at 4 weeks, 6 or 12 months after surgery.
conclusionIn contrast to previous studies in patients with colonic cancer, HRQL after rectal cancer surgery was not affected by surgical approach. REGISTRATION NUMBER: NCT00297791 (http://www.clinicaltrials.gov).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.