ArticleZeitschrift fur Rheumatologie2013
[Histopathology and microbiology of joint infections: extension of diagnostic safety in patients with chronic polyarthritis].
Article in Zeitschrift fur Rheumatologie, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- [Histopathological diagnostics of infections in rheumatology].Zeitschrift fur Rheumatologie · 2025Review
- [Periprosthetic and interprothetic fractures in patients with rheumatism : Characteristics of conservative and surgical treatment].Der Unfallchirurg · 2020Review
- Three-year follow-up of changes of cortical bone thickness after implantation of Endo-Exo-Prosthesis (EEP) for transfemoral amputees.Journal of orthopaedic surgery and research · 2020Article
- [Histopathological classification principles of rheumatic joint diseases : Contribution of pathology to the diagnosis].Der Orthopade · 2018Review
- Assay of Blood and Synovial Fluid of Patients With Rheumatoid Arthritis for Staphylococcus aureus Enterotoxin D: Absence of Bacteria But Presence of Its Toxin.Jundishapur journal of microbiology · 2015Article
- [Revision arthroplasty : Histopathological diagnostics in periprosthetic joint infections].Der Orthopade · 2015Article
- [Periprosthetic infections in systemic inflammatory rheumatic disease. Review article on diagnostics and therapy].Zeitschrift fur Rheumatologie · 2014Review
- Histopathological Osteomyelitis Evaluation Score (HOES) - an innovative approach to histopathological diagnostics and scoring of osteomyelitis.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt can be difficult to distinguish between synovitis due to rheumatism and synovitis due to a bacterial infection. Microbiological detection of bacteria is not always successful and the clinical significance of low virulent bacteria often remains uncertain. Therefore, the histopathological finding of inflammatory reactions is very important. STUDY DESIGN AND
methodsFrom patients with clinically clear signs of infections and rheumatoid arthritis who underwent surgery between April and August 2011, samples were taken during surgery. Histopathological diagnosis was carried out by conventional enzyme and immunohistochemical techniques based on defined criteria of bacterial infection in tissues, synovial tissue and bone.
resultsA total of 20 patients were included, 10 males and 10 females with a mean age of 61.7 years. Staphylococcus aureus was the most commonly detected bacteria and in 4 cases bacteria could not be demonstrated. The correlation between the histopathological signs of an infection and microbiological detection of bacteria was 93.3 %.
conclusionsIn patients with rheumatoid arthritis the combination of histopathology and microbiology significantly increased the safety of detecting an infection or contamination.
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