ArticleJournal of neuro-oncology2013
Neurocognitive functioning and health-related quality of life in patients with radiologically suspected meningiomas.
Article in Journal of neuro-oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 7 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 7 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Health-related quality-of-life outcomes in CNS WHO grade 2 and 3 meningioma: a systematic review.Neurosurgical review · 2025Pooled it
- The unseen impact - a deep dive into neurocognitive impairment among patients with intracranial meningiomas: a comprehensive systematic review of the literature.Neurosurgical review · 2024Pooled it
- EANO guideline on the diagnosis and management of meningiomas.Neuro-oncology · 2021Guideline
- Incidental intracranial meningiomas: a systematic review and meta-analysis of prognostic factors and outcomes.Journal of neuro-oncology · 2019Pooled it
- Impaired health-related quality of life in meningioma patients-a systematic review.Neuro-oncology · 2017Pooled it
- Cognitive functioning in meningioma patients: a systematic review.Journal of neuro-oncology · 2016Pooled it
- Pooled it
- Gut Microbiota Influences Meningioma Pathogenesis via Circulating Metabolites: A Two-Sample Mendelian Randomization Study.Brain and behavior · 2025Article
- Neurocognitive evaluation in patients with intracranial Meningiomas: A systematic review.Brain & spine · 2025Review
- Health-related quality of life in surgically treated asymptomatic meningioma patients: A population-based matched cohort study.Neuro-oncology practice · 2024Article
- Preoperative executive functioning impairments in patients with a meningioma: does a frontal location matter?Brain imaging and behavior · 2024Article
- Review
- Multiple meningiomas: Epidemiology, management, and outcomes.Neuro-oncology advances · 2023Article
- Brain Tumor at Diagnosis: From Cognition and Behavior to Quality of Life.Diagnostics (Basel, Switzerland) · 2023Review
- Meningiomas with CNS invasion.Frontiers in neuroscience · 2023Review
- Health-Related Quality of Life in Intracranial Meningioma: Current Evidence and Future Directions.Advances in experimental medicine and biology · 2023Article
- Prevalence, correlates, and impact of sleep disturbance in Chinese meningioma patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Symptom burden and surgical outcome in non-skull base meningiomas.Frontiers in oncology · 2022Article
- Article
- A prognostic model to personalize monitoring regimes for patients with incidental asymptomatic meningiomas.Neuro-oncology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Few data are available concerning the neurocognitive outcome and health-related quality of life (HRQOL) following neurosurgery in meningioma patients, and even less is known about neurocognitive functioning and HRQOL in untreated patients with stable lesions. The present study aims at quantifying the nature and extent of neurocognitive deficits and HRQOL in suspected WHO grade I meningioma patients who have not received surgery and/or radiotherapy and compare outcome to that of healthy controls. Neurocognitive functioning was assessed by using a standardized test battery in 21 radiologically suspected WHO grade I meningioma patients with a wait-and-scan approach. HRQOL was assessed with the MOS SF-36 questionnaire. These patients were matched for age, sex, and education with 21 healthy controls. Associations between neurocognitive functioning on the one hand and HRQOL and tumor characteristics on the other were determined. Compared to healthy controls, meningioma patients had lower psychomotor speed (p = 0.011) and working memory capacity (p = 0.034) and furthermore attained lower levels of self-perceived general health and vitality. Neurocognitive functioning in untreated patients was not related to tumor volume, edema or tumor lateralization. No correlations were found between psychomotor speed or working memory and HRQOL. Untreated meningioma patients with stable lesions have limitations in neurocognitive functioning and HRQOL. In deciding upon a treatment strategy these reductions in functioning should be taken into consideration and communicated with the patient.
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