Evidence map›Paper›PMID 23640084›Full record

ArticlePhysics in medicine and biology2013

Photo-magnetic imaging: resolving optical contrast at MRI resolution.

Yuting Lin, Hao Gao, David Thayer, Alex L Luk, Gultekin Gulsen

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Real-time photo-magnetic imaging.Biomedical optics express · 2016
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuting LinTu and Yuen Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, USA. yutingl@uci.edu
Hao Gao
David Thayer
Alex L Luk
Gultekin Gulsen

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
Development of A Multi-Modality System for Onco-ImagingR33CA120175 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2008 to 2010
$1.5M
Tomographic Molecular Imaging for Breast CancerR01EB008716 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2008 to 2011
$1.3M
Fluorescence Tomography in Small Animal Imaging using an Ultra-fast RTE SolverR21EB013387 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GAO, HAO · 2011 to 2012
$345k
Development of A Multi-Modality System for Onco-ImagingR21CA120175 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2007 to 2007
$225k
Photomagnetic Imaging: A Novel Modality for Cancer ImagingF31CA171745 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI LUK, ALEX T · 2013 to 2015
$128k
NCI NIH HHS F31 CA171745NCI NIH HHS P30 CA062203NCI NIH HHS R01CA1429898NCI NIH HHS R21/33 CA120175NCI NIH HHS R21 CA120175NCI NIH HHS R33 CA120175NIBIB NIH HHS R01 EB008716NIBIB NIH HHS R01EB008716NIBIB NIH HHS R21 EB013387NIBIB NIH HHS R21EB013387
6 · The paper itself

Abstract

In this paper, we establish the mathematical framework of a novel imaging technique, namely photo-magnetic imaging (PMI). PMI uses a laser to illuminate biological tissues and measure the induced temperature variations using magnetic resonance imaging (MRI). PMI overcomes the limitation of conventional optical imaging and allows imaging of the optical contrast at MRI spatial resolution. The image reconstruction for PMI, using a finite-element-based algorithm with an iterative approach, is presented in this paper. The quantitative accuracy of PMI is investigated for various inclusion sizes, depths and absorption values. Then, a comparison between conventional diffuse optical tomography (DOT) and PMI is carried out to illustrate the superior performance of PMI. An example is presented showing that two 2 mm diameter inclusions embedded 4.5 mm deep and located side by side in a 25 mm diameter circular geometry medium are recovered as a single 6 mm diameter object with DOT. However, these two objects are not only effectively resolved with PMI, but their true concentrations are also recovered successfully.

Indexed as

Optical PhenomenaAbsorptionDiffusionHot TemperatureMagnetic Resonance ImagingModels, TheoreticalMotionPhantoms, ImagingPhotons

Identifiers

PMID23640084
PMCPMC4031318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.