ArticleJournal of biomedical optics2013
Dual-wavelength photothermal optical coherence tomography for imaging microvasculature blood oxygen saturation.
Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Photothermal optical coherence tomography for 3D live cell detection and mapping.Optics continuum · 2023Article
- Adaptive spectroscopic visible-light optical coherence tomography for clinical retinal oximetry.Communications medicine · 2023Article
- Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries.Biomedical optics express · 2022Article
- Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography.Journal of biomedical optics · 2021Review
- LongitudinalJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Fourier phase in Fourier-domain optical coherence tomography.Journal of the Optical Society of America. A, Optics, image science, and vision · 2015Article
- Monitoring photodynamic therapy with photoacoustic microscopy.Journal of biomedical optics · 2015Article
- Photothermal optical lock-in optical coherence tomography for in vivo imaging.Biomedical optics express · 2015Article
- Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography.Biomedical optics express · 2015Article
- Molecular Imaging in Optical Coherence Tomography.Current molecular imaging · 2014Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
A swept-source dual-wavelength photothermal (DWP) optical coherence tomography (OCT) system is demonstrated for quantitative imaging of microvasculature oxygen saturation. DWP-OCT is capable of recording three-dimensional images of tissue and depth-resolved phase variation in response to photothermal excitation. A 1,064-nm OCT probe and 770-nm and 800-nm photothermal excitation beams are combined in a single-mode optical fiber to measure microvasculature hemoglobin oxygen saturation (SO(2)) levels in phantom blood vessels with a range of blood flow speeds (0 to 17 mm/s). A 50-μm-diameter blood vessel phantom is imaged, and SO(2) levels are measured using DWP-OCT and compared with values provided by a commercial oximeter at various blood oxygen concentrations. The influences of blood flow speed and mechanisms of SNR phase degradation on the accuracy of SO(2) measurement are identified and investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.