ArticleNeuroscience2013
Remodeling sensory cortical maps implants specific behavioral memory.
Article in Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Electrical stimulation of the nucleus basalis of meynert: a systematic review of preclinical and clinical data.Scientific reports · 2021Pooled it
- Generalization of fear learning is shaped by inhibitory sensory processing in mice.Nature communications · 2026Article
- Functional diversities within neurons and astrocytes in the adult rat auditory cortex revealed by single-nucleus RNA sequencing.Scientific reports · 2024Article
- Learning induces unique transcriptional landscapes in the auditory cortex.Hearing research · 2023Review
- High trait anxiety blocks olfactory plasticity induced by aversive learning.Biological psychology · 2022Article
- Precise memory for pure tones is predicted by measures of learning-induced sensory system neurophysiological plasticity at cortical and subcortical levels.Learning & memory (Cold Spring Harbor, N.Y.) · 2020Article
- Pairing vagus nerve stimulation with tones drives plasticity across the auditory pathway.Journal of neurophysiology · 2019Article
- State-dependent encoding of sound and behavioral meaning in a tertiary region of the ferret auditory cortex.Nature neuroscience · 2019Article
- Kinase activity in the olfactory bulb is required for odor memory consolidation.Learning & memory (Cold Spring Harbor, N.Y.) · 2018Article
- Brief Stimulus Exposure Fully Remediates Temporal Processing Deficits Induced by Early Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Sensory Cortical Plasticity Participates in the Epigenetic Regulation of Robust Memory Formation.Neural plasticity · 2016Review
- Learning strategy refinement reverses early sensory cortical map expansion but not behavior: Support for a theory of directed cortical substrates of learning and memory.Neurobiology of learning and memory · 2015Article
- Associative learning and sensory neuroplasticity: how does it happen and what is it good for?Learning & memory (Cold Spring Harbor, N.Y.) · 2015Review
- Extinction reverses olfactory fear-conditioned increases in neuron number and glomerular size.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Histone Deacetylase Inhibition via RGFP966 Releases the Brakes on Sensory Cortical Plasticity and the Specificity of Memory Formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Relational associative learning induces cross-modal plasticity in early visual cortex.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Cortical Synaptic Inhibition Declines during Auditory Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Auditory cortex is required for fear potentiation of gap detection.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Auditory map plasticity: diversity in causes and consequences.Current opinion in neurobiology · 2014Review
- Neuromusic research: some benefits of incorporating basic research on the neurobiology of auditory learning and memory.Frontiers in systems neuroscience · 2013Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Neural mechanisms underlying the capacity of memory to be rich in sensory detail are largely unknown. A candidate mechanism is learning-induced plasticity that remodels the adult sensory cortex. Here, expansion in the primary auditory cortical (A1) tonotopic map of rats was induced by pairing a 3.66-kHz tone with activation of the nucleus basalis, mimicking the effects of natural associative learning. Remodeling of A1 produced de novo specific behavioral memory, but neither memory nor plasticity was consistently at the frequency of the paired tone, which typically decreased in A1 representation. Rather, there was a specific match between individual subjects' area of expansion and the tone that was strongest in each animal's memory, as determined by post-training frequency generalization gradients. These findings provide the first demonstration of a match between the artificial induction of specific neural representational plasticity and artificial induction of behavioral memory. As such, together with prior and present findings for detection, correlation and mimicry of plasticity with the acquisition of memory, they satisfy a key criterion for neural substrates of memory. This demonstrates that directly remodeling sensory cortical maps is sufficient for the specificity of memory formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.