ReviewTransplantation reviews (Orlando, Fla.)2013
Immunosenescence and organ transplantation.
Review in Transplantation reviews (Orlando, Fla.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Infections after kidney transplantation. Does age matter?Clinical transplantation · 2019Trial
- Cellular Immunity in Chronic Kidney Disease and Changes After Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Necessity of induction agent modification for old age kidney transplant recipients.Kidney research and clinical practice · 2025Article
- Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina.Frontiers in aging · 2025Article
- Impact of Immunosenescence in Older Kidney Transplant Recipients: Associated Clinical Outcomes and Possible Risk Stratification for Immunosuppression Reduction.Drugs & aging · 2024Review
- Editorial: Immunosenescence in organ transplantation.Frontiers in transplantation · 2024Article
- Can We Predict Graft Intolerance Syndrome After Kidney Transplant Failure? External Validation of a Previously Developed Model.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Current perspective of immunomodulators for lung transplant.Indian journal of thoracic and cardiovascular surgery · 2022Review
- Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality.Kidney research and clinical practice · 2022Article
- Clinical perspectives on the age-related increase of immunosuppressive activity.Journal of molecular medicine (Berlin, Germany) · 2022Review
- Can Gene Expression Analysis in Zero-Time Biopsies Predict Kidney Transplant Rejection?Frontiers in medicine · 2022Article
- Heart Transplant in Older Adults.Current transplantation reports · 2022Review
- Review: immunosuppression for the lung transplant patient.Journal of thoracic disease · 2021Review
- Immunosuppression Considerations for Older Kidney Transplant Recipients.Current transplantation reports · 2021Article
- Leukocyte transcriptome indicators of development of infection in kidney transplant recipients.Clinical transplantation · 2021Article
- CTLA4-Ig prolongs graft survival specifically in young but not old mice.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Targeting age-specific changes in CD4Aging cell · 2021Article
- Pharmacokinetic and Pharmacodynamic Considerations in Relation to Calcineurin Usage in Elderly Kidney Transplant Recipients.Frontiers in pharmacology · 2021Review
- Solid organ transplantation in older adults. Infectious and other age-related considerations.OBM transplantation · 2019Article
- Changes of T-cell Immunity Over a Lifetime.Transplantation · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Increasing numbers of elderly transplant recipients and a growing demand for organs from older donors impose pressing challenges on transplantation medicine. Continuous and complex modifications of the immune system in parallel to aging have a major impact on transplant outcome and organ quality. Both, altered alloimmune responses and increased immunogenicity of organs present risk factors for inferior patient and graft survival. Moreover, a growing body of knowledge on age-dependent modifications of allorecognition and alloimmune responses may require age-adapted immunosuppression and organ allocation. Here, we summarize relevant aspects of immunosenescence and their possible clinical impact on organ transplantation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.