ArticleDisability and rehabilitation2014
Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project.
Article in Disability and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Multiple joint osteoarthritis (MJOA): What's in a name?Osteoarthritis and cartilage · 2024Review
- Incidence and progression of ankle osteoarthritis: The johnston county osteoarthritis project.Seminars in arthritis and rheumatism · 2021Article
- Article
- Functional outcome measures in a surgical model of hip osteoarthritis in dogs.Journal of experimental orthopaedics · 2016Article
- The clinical burden of generalized osteoarthritis represented by self-reported health-related quality of life and activity limitations: a cross-sectional study.Rheumatology international · 2015Article
- Early surrender to knee arthroplasty.... Not so fast.... Let the knee tissue preservation and function sustainability dialogue begin!Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Article
- Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
purposeTo determine associations between multiple joint symptoms and radiographic osteoarthritis (rOA) and functional outcomes.
methodComplete cross-sectional data for multi-joint symptoms and radiographs, Health Assessment Questionnaire (HAQ) scores, and gait speed were available for 1307 Johnston County Osteoarthritis Project participants (34% men, 32% African American, mean age 66 years). Factor analysis of symptom scores and radiographic grades for the lumbosacral spine, bilateral hands, knees, and hips provided composite scores. Regression models were used to determine associations between composite scores, HAQ, and gait speed, adjusting for age, body mass index, gender, and race.
resultsFive rOA factors were identified: (1) IP/CMC factor (carpometacarpal [CMC] and all interphalangeal [IP] joints); (2) MCP factor (metacarpophalangeal joints 2-5); (3) Knee factor (tibiofemoral and patellofemoral joints); (4) Spine factor (L1/2 to L5/S1); and (5) Symptom factor. After adjustment, only the Symptom composite was significantly associated with HAQ and gait speed; a 1-standard deviation increase in Symptom score was associated with 9 times higher odds of having poorer function on the HAQ (odds ratio 9.32, 95% confidence interval [CI] 6.80, 12.77), and a clinically significant decline in gait speed (0.06 m/s, 95% CI -0.07, -0.05).
conclusionsA novel Symptom composite score was associated with poorer functional outcomes. IMPLICATIONS FOR REHABILITATION: Osteoarthritis (OA) commonly affects multiple joints and is the most common form of arthritis. Symptomatic assessments, which can be easily executed by rehabilitation practitioners, are more closely related to self-reported and performance-based functional status than are less accessible and more costly radiographs. Symptomatic assessments are likely to be more informative for understanding, treating, and potentially preventing functional limitations than radiographic assessments.
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