ArticleNano letters2013
Intracellular SERS nanoprobes for distinction of different neuronal cell types.
Article in Nano letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Magnetic field-induced plasmonic enhancement of near infrared fluorescence from a Magnetoplasmonic nanoplatform for bioimaging applications.Journal of nanobiotechnology · 2025Article
- Plasmonic Biosensors in Cancer-Associated miRNA Detection.Biosensors · 2025Review
- Monitoring lipopolysaccharide-induced macrophage polarization by surface-enhanced Raman scattering.Mikrochimica acta · 2024Article
- A Scaffold-Assisted 3D Cancer Cell Model for Surface-Enhanced Raman Scattering-Based Real-Time Sensing and Imaging.ACS nano · 2024Article
- Recent advances in SERS-based bioanalytical applications: live cell imaging.Nanophotonics (Berlin, Germany) · 2024Review
- Convection-enhanced delivery of nanoencapsulated gene locoregionally yielding ErbB2/Her2-specific CAR-macrophages for brainstem glioma immunotherapy.Journal of nanobiotechnology · 2023Article
- Surface-enhanced Raman scattering: An emerging tool for sensing cellular function.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022Review
- Review
- Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: a review.Chemical Society reviews · 2022Review
- Live Cell Poration by Au Nanostars to Probe Intracellular Molecular Composition with SERS.Nanomaterials (Basel, Switzerland) · 2021Article
- Random Lasing Detection of Mutant Huntingtin Expression in Cells.Sensors (Basel, Switzerland) · 2021Article
- Furin-Mediated Self-Assembly of Olsalazine Nanoparticles for Targeted Raman Imaging of Tumors.Angewandte Chemie (International ed. in English) · 2021Article
- Recent advances in nanomaterial-based biosensors for the detection of exosomes.Analytical and bioanalytical chemistry · 2021Review
- Recent progress of surface-enhanced Raman spectroscopy for subcellular compartment analysis.Theranostics · 2021Review
- Imaging of PD-L1 in single cancer cells by SERS-based hyperspectral analysis.Biomedical optics express · 2020Article
- Serum Raman spectroscopy as a diagnostic tool in patients with Huntington's disease.Chemical science · 2020Article
- Metallic Nanoparticle-Based Optical Cell Chip for Nondestructive Monitoring of Intra/Extracellular Signals.Pharmaceutics · 2020Review
- Scalable nanolaminated SERS multiwell cell culture assay.Microsystems & nanoengineering · 2020Article
- The label-free detection and distinction of CYP2C9-expressing and non-expressing cells by surface-enhanced Raman scattering substrates based on bimetallic AuNPs-AgNWs.RSC advances · 2019Article
- On-Demand Intracellular Delivery of Single Particles in Single Cells by 3D Hollow Nanoelectrodes.Nano letters · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Distinction between closely related and morphologically similar cells is difficult by conventional methods especially without labeling. Using nuclear-targeted gold nanoparticles (AuNPs) as intracellular probes we demonstrate the ability to distinguish between progenitor and differentiated cell types in a human neuroblastoma cell line using surface-enhanced Raman spectroscopy (SERS). SERS spectra from the whole cell area as well as only the nucleus were analyzed using principal component analysis that allowed unambiguous distinction of the different cell types. SERS spectra from the nuclear region showed the developments during cellular differentiation by identifying an increase in DNA/RNA ratio and proteins transcribed. Our approach using nuclear-targeted AuNPs and SERS imaging provides label-free and noninvasive characterization that can play a vital role in identifying cell types in biomedical stem cell research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.