ArticlePeerJ2013
Regulation of the heat stress response in Arabidopsis by MPK6-targeted phosphorylation of the heat stress factor HsfA2.
Article in PeerJ, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed.
- Principles and mechanisms of plant acclimation to heat stress.Nature reviews. Molecular cell biology · 2026Review
- Integrating molecular networks and physiological adaptation for heat-resilient crops.Journal of integrative plant biology · 2026Review
- Adaptive response to long-term high temperatures during the reproductive development in Arabidopsis thaliana.Planta · 2026Article
- The dual role of PORC in chloroplast thermotolerance.Plant physiology · 2026Article
- From Perception to Adaptation: A Comparative Study of Plant Regulatory Networks in Response to Heat and Waterlogging Stress.Plants (Basel, Switzerland) · 2026Review
- Review
- Integrated analysis of physiological responses and transcriptional regulation in kiwifruit under high temperature.BMC plant biology · 2025Article
- Advances in Protein Kinase Regulation of Stress Responses in Fruits and Vegetables.International journal of molecular sciences · 2025Review
- ZmHSFA2B self-regulatory loop is critical for heat tolerance in maize.Plant biotechnology journal · 2025Article
- Genome-Wide Characterization of the Heat Shock Transcription Factor Gene Family inInternational journal of molecular sciences · 2024Article
- Phosphorylation of auxin signaling repressor IAA8 by heat-responsive MPKs causes defective flower development.Plant physiology · 2024Article
- MaHsf24, a novel negative modulator, regulates cold tolerance in banana fruits by repressing the expression of HSPs and antioxidant enzyme genes.Plant biotechnology journal · 2024Article
- Proteomic profiling of Arabidopsis nuclei reveals distinct protein accumulation kinetics upon heat stress.Scientific reports · 2024Article
- Genome-Wide Analysis of theInternational journal of molecular sciences · 2024Article
- ZmMKK9-ZmMPK20-ZmRIN2 cascade boosts plant heat tolerance by regulating stomatal response.Plant cell reports · 2024Article
- Article
- Calcium Signaling and the Response to Heat Shock in Crop Plants.International journal of molecular sciences · 2023Review
- OsMAPK6 positively regulates rice cold tolerance at seedling stage via phosphorylating and stabilizing OsICE1 and OsIPA1.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Shade-induced RTFL/DVL peptides negatively regulate the shade response by directly interacting with BSKs in Arabidopsis.Nature communications · 2023Article
- Transcriptional Regulation of Small Heat Shock Protein 17 (sHSP-17) byPlants (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
So far little is known on the functional role of phosphorylation in the heat stress response of plants. Here we present evidence that heat stress activates the Arabidopsis mitogen-activated protein kinase MPK6. In vitro and in vivo evidence is provided that MPK6 specifically targets the major heat stress transcription factor HsfA2. Activation of MPK6 results in complex formation with HsfA2. MPK6 phosphorylates HsfA2 on T249 and changes its intracellular localisation. Protein kinase and phosphatase inhibitor studies indicate that HsfA2 protein stability is regulated in a phosphorylation-dependent manner, but this mechanism is independent of MPK6. Overall, our data show that heat stress-induced targeting of HsfA2 by MPK6 participates in the complex regulatory mechanism how plants respond to heat stress.
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