ArticlePloS one2013
Role of baseline antral follicle count and anti-Mullerian hormone in prediction of cumulative live birth in the first in vitro fertilisation cycle: a retrospective cohort analysis.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 104 citations in OpenAlex.
- Randomized controlled study on the use of virtual reality for pain relief in oocyte retrieval under transvaginal ultrasound guidance using paracervical block and conscious sedation.Human reproduction (Oxford, England) · 2025Trial
- Nomogram for the cumulative live birth in women undergoing the first IVF cycle: Base on 26, 689 patients in China.Frontiers in endocrinology · 2022Trial
- Trial
- The Relation between Celiac Disease and Ovarian Reserve: A Case-Control Study.International journal of fertility & sterility · 2025Article
- Effect of pre-conception serum vitamin D level on pregnancy outcomes in women undergoing in vitro fertilization with fresh embryo transfer: a retrospective analysis.Reproductive biology and endocrinology : RB&E · 2025Article
- Age-stratified anti-Müllerian hormone (AMH) nomogram: a comprehensive cohort study including 22.920 women.Frontiers in endocrinology · 2025Article
- Total Fertilization Failure: A Single Center Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Personalized prediction of the secondary oocytes number after ovarian stimulation: A machine learning model based on clinical and genetic data.PLoS computational biology · 2023Article
- Analysis of cumulative outcomes and influencing factors of patients with discrepancies between age and AMH levels in the early follicular phase prolonged protocol.Frontiers in endocrinology · 2023Article
- Comparison of the prevalence and severity of nausea and vomiting in the first trimester between singleton pregnancies conceived from stimulated in vitro fertilization and frozen embryo transfer cycles.BMC pregnancy and childbirth · 2022Article
- Article
- Are There Ovarian Responsive Indexes That Predict Cumulative Live Birth Rates in Women over 39 Years?Journal of clinical medicine · 2022Article
- 100 YEARS OF VITAMIN D: Effect of serum vitamin D level before ovarian stimulation on the cumulative live birth rate of women undergoing in vitro fertilization: a retrospective analysis.Endocrine connections · 2022Article
- Machine Learning-Based Modeling of Ovarian Response and the Quantitative Evaluation of Comprehensive Impact Features.Diagnostics (Basel, Switzerland) · 2022Article
- Women in Advanced Reproductive Age: Are the Follicular Output Rate, the Follicle-Oocyte Index and the Ovarian Sensitivity Index Predictors of Live Birth in an IVF Cycle?Journal of clinical medicine · 2022Article
- Effects of follicular output rate on cumulative clinical pregnancy rate and cumulative live birth rate in PCOS patients with different characteristics.Frontiers in endocrinology · 2022Article
- Ovarian Sensitivity Decreased Significantly in Patients With Insulin Resistance UndergoingFrontiers in physiology · 2021Article
- Body Mass Index Showed No Impact on the Outcome of In Vitro Fertilization in Progestin-Primed Ovarian Stimulation Protocol.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Anti-Müllerian hormone is correlated with cumulative live birth in minimal ovarian stimulation with clomiphene citrate: a retrospective cohort study.BMC pregnancy and childbirth · 2020Article
- The Ovarian Sensitivity Index (OSI) Significantly Correlates with Ovarian Reserve Biomarkers, Is More Predictive of Clinical Pregnancy than the Total Number of Oocytes, and Is Consistent in Consecutive IVF Cycles.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis retrospective study determined for the first time the role of baseline antral follicle count (AFC) and serum anti-Mullerian hormone (AMH) level in the first in-vitro fertilisation (IVF) cycle in predicting cumulative live birth from one stimulation cycle.
methodsWe studied 1,156 women (median age 35 years) undergoing the first IVF cycle. Baseline AFC and AMH level on the day before ovarian stimulation were analysed. The main outcome measure was cumulative live birth in the fresh plus all the frozen embryo transfers after the same stimulation cycle.
resultsSerum AMH was significantly correlated with AFC. Both AMH and AFC showed significant correlation with age and ovarian response in the stimulated cycle and total number of transferrable embryos. Baseline AFC and serum AMH were significantly higher in subjects attaining a live birth than those who did not in the fresh stimulated cycle, as well as those attaining cumulative live birth. There was a significant trend of higher cumulative live birth rate in women with higher AMH or AFC. However, logistic regression revealed that both AMH and AFC were not significant predictors of cumulative live birth after adjusting for age and number of embryos available for transfer. Considering only one single predictor, the areas under the ROC curves for AMH (0.646, 95% CI 0.616-0.675) and age (0.648, 95% CI 0.618-0.677) were slightly higher than that for AFC (0.617, 95% CI 0.587-0.647) in predicting cumulative live birth. However, a model combining AMH (with or without AFC) and age of the women only classified an addition of less than 2% of subjects correctly compared to the model with age alone.
conclusionBaseline AFC and serum AMH have only modest predictive performance on the occurrence of cumulative live birth, and may not give additional value on top of the women's age.
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