ArticlePloS one2013
The baboon kidney transcriptome: analysis of transcript sequence, splice variants, and abundance.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- The Baboon as a Model to Study Human Health and Complex Disease.American journal of primatology · 2026Review
- Liver molecular networks associated with drinking behavior in nonhuman primates.Alcohol, clinical & experimental research · 2025Article
- Article
- Maternal under-nutrition during pregnancy alters the molecular response to over-nutrition in multiple organs and tissues in nonhuman primate juvenile offspring.Journal of developmental origins of health and disease · 2024Article
- Integrated multi-omics analysis of brain aging in female nonhuman primates reveals altered signaling pathways relevant to age-related disorders.Neurobiology of aging · 2023Article
- Cell-type deconvolution of bulk RNA-Seq from kidney using opensource bioinformatic tools.bioRxiv : the preprint server for biology · 2023Article
- Postnatal persistence of nonhuman primate sex-dependent renal structural and molecular changes programmed by intrauterine growth restriction.Journal of medical primatology · 2022Article
- Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates.Physiological genomics · 2022Article
- Circulating miRNAs associated with bone mineral density in healthy adult baboons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
- Hepatic transcript signatures predict atherosclerotic lesion burden prior to a 2-year high cholesterol, high fat diet challenge.PloS one · 2022Article
- Integrated omics analysis reveals sirtuin signaling is central to hepatic response to a high fructose diet.BMC genomics · 2021Article
- Skeletal muscle extracellular matrix remodeling with worsening glycemic control in nonhuman primates.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Identification of coordinately regulated microRNA-gene networks that differ in baboons discordant for LDL-cholesterol.PloS one · 2019Article
- De novo transcriptomic analysis and development of EST-SSR markers in the Siberian tiger (Panthera tigris altaica).Molecular genetics and genomics : MGG · 2016Article
- Myosin 1b Regulates Amino Acid Transport by Associating Transporters with the Apical Plasma Membrane of Kidney Cells.PloS one · 2015Article
- Article
- Characterization of the kidney transcriptome of the South American olive mouse Abrothrix olivacea.BMC genomics · 2014Article
- Baboons as a model to study genetics and epigenetics of human disease.ILAR journal · 2013Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The baboon is an invaluable model for the study of human health and disease, including many complex diseases of the kidney. Although scientists have made great progress in developing this animal as a model for numerous areas of biomedical research, genomic resources for the baboon, such as a quality annotated genome, are still lacking. To this end, we characterized the baboon kidney transcriptome using high-throughput cDNA sequencing (RNA-Seq) to identify genes, gene variants, single nucleotide polymorphisms (SNPs), insertion-deletion polymorphisms (InDels), cellular functions, and key pathways in the baboon kidney to provide a genomic resource for the baboon. Analysis of our sequencing data revealed 45,499 high-confidence SNPs and 29,813 InDels comparing baboon cDNA sequences with the human hg18 reference assembly and identified 35,900 cDNAs in the baboon kidney, including 35,150 transcripts representing 15,369 genic genes that are novel for the baboon. Gene ontology analysis of our sequencing dataset also identified numerous biological functions and canonical pathways that were significant in the baboon kidney, including a large number of metabolic pathways that support known functions of the kidney. The results presented in this study catalogues the transcribed mRNAs, noncoding RNAs, and hypothetical proteins in the baboon kidney and establishes a genomic resource for scientists using the baboon as an experimental model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.