Evidence map›Paper›PMID 23637552›Full record

ArticleInternational journal of general medicine2013

Review of evidence for immune evasion and persistent infection in Lyme disease.

Keith Berndtson

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 73 citations in OpenAlex.

  1. Microbes and Mental Illness: Past, Present, and Future.Healthcare (Basel, Switzerland) · 2023
    Review
  2. Concurrent Infection of the Human Brain with MultipleInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Pleomorphic Variants ofInternational journal of molecular sciences · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Antibiotics (Basel, Switzerland) · 2020
    Article
  15. Article
  16. Article
  17. Article
  18. Lyme Disease Frontiers: ReconcilingPathogens (Basel, Switzerland) · 2019
    Review
  19. Detection and Transstadial Passage ofHealthcare (Basel, Switzerland) · 2019
    Article
  20. The Long-Term Persistence ofAntibiotics (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Keith BerndtsonPark Ridge MultiMed, Park Ridge, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Is chronic illness in patients with Lyme disease caused by persistent infection? Three decades of basic and clinical research have yet to produce a definitive answer to this question. This review describes known and suspected mechanisms by which spirochetes of the Borrelia genus evade host immune defenses and survive antibiotic challenge. Accumulating evidence indicates that Lyme disease spirochetes are adapted to persist in immune competent hosts, and that they are able to remain infective despite aggressive antibiotic challenge. Advancing understanding of the survival mechanisms of the Lyme disease spirochete carry noteworthy implications for ongoing research and clinical practice.

Indexed as

antibiotic tolerancebacterial persistencebiofilmBorreliaLyme disease

Identifiers

PMID23637552
PMCPMC3636972
OpenAlexW2136310274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.