Evidence map›Paper›PMID 23636741›Full record

ArticleGenetics2013

The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.

Bungo Akiyoshi, Christian R Nelson, Sue Biggins

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 70 citations in OpenAlex.

  1. An interdependent Cbf1-CCAN interaction stabilizes the budding yeast kinetochore.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Binding site maturation modulated by molecular density underlies Ndc80 binding to kinetochore receptor CENP-T.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Meiosis-specific decoupling of the pericentromere from the kinetochore.bioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Structure of the human outer kinetochore KMN network complex.Nature structural & molecular biology · 2024
    Article
  13. Review
  14. Kinetochore Architecture Employs Diverse Linker Strategies Across Evolution.Frontiers in cell and developmental biology · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bungo AkiyoshiMolecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA.
Christian R Nelson
Sue Biggins
Fred Hutch Cancer Center · USUniversity of Washington · US

Funding

Regulation of Chromosome SegregationR01GM064386 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BIGGINS, SUSAN · 2002 to 2022
$7.2M
Regulation of Centromeric ChromatinR01GM078069 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BIGGINS, SUSAN · 2007 to 2015
$2.7M
Genome wide analysis and modeling of signal integration in the Drosophila ovaryR01GM078079 · NIGMS · PRINCETON UNIVERSITY · PI SHVARTSMAN, STANISLAV Y. · 2006 to 2009
$978k
NIGMS NIH HHS GM064386NIGMS NIH HHS GM078079NIGMS NIH HHS R01 GM064386NIGMS NIH HHS R01 GM078069NIGMS NIH HHS R01 GM078079
6 · The paper itself

Abstract

The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast.

Indexed as

Chromosome SegregationAurora Kinase BChromosomal Proteins, Non-HistoneGene Expression Regulation, FungalKinetochoresMicrotubulesMitosisNuclear ProteinsPhosphorylationProtein Interaction MapsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAurora Kinase BChromosomal Proteins, Non-HistoneDsn1 protein, S cerevisiaeNuclear ProteinsSaccharomyces cerevisiae Proteinschromosome segregationDsn1Ipl1/Aurora B protein kinasekinetochore

Identifiers

PMID23636741
PMCPMC3697981
OpenAlexW2106320311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.