ArticleLipids2013
New long chain bases in lipophosphonoglycan of Acanthamoeba castellanii.
Article in Lipids, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Lipidomics Analysis of Multilamellar Bodies Produced by AmoebaPathogens (Basel, Switzerland) · 2023Article
- Extracellular Vesicles from the ProtozoaBioengineering (Basel, Switzerland) · 2019Review
- Glycoconjugates of Gram-negative bacteria and parasitic protozoa - are they similar in orchestrating the innate immune response?Innate immunity · 2019Review
- A Mutation in theInternational journal of molecular sciences · 2018Article
- Acanthamoeba Activates Macrophages Predominantly through Toll-Like Receptor 4- and MyD88-Dependent Mechanisms To Induce Interleukin-12 (IL-12) and IL-6.Infection and immunity · 2017Article
- Growth and Survival of Mesorhizobium loti Inside Acanthamoeba Enhanced Its Ability to Develop More Nodules on Lotus corniculatus.Microbial ecology · 2015Article
- Interactions between Human Norovirus Surrogates and Acanthamoeba spp.Applied and environmental microbiology · 2015Article
- Ether-type moieties in the lipid part of glycoinositolphospholipids of Acanthamoeba rhysodes.Lipids · 2014Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The polymer called lipophosphonoglycan (LPG) was isolated from Acanthamoeba castellanii membranes after exhaustive delipidation and butanol extraction. A novel extremely long phytosphingosine was revealed in glycoinositolphosphosphingolipid (GIPSL). All data obtained by gas-liquid chromatography coupled with MS analyses of products liberated during acid methanolysis and products of sodium metaperiodate and permanganate-periodate oxidations showed an unusual pattern of long chain bases (LCB) with branched bases (anteiso-C₂₄, anteiso-C₂₅, anteiso-C₂₆, iso-C₂₆, anteiso-C₂₇, and anteiso-C28) and normal ones (C₂₄, C₂₅, C₂₆, C₂₇). The phytosphingosines with hexa-, hepta-, and octacosanoic chains have not been detected in Acanthamoeba cells up to now. Also, the isomer configuration of long chain bases in LPG of A. castellanii was not defined in earlier reports. In the GC-MS chromatograms, the component forming a peak corresponding to anteiso-C₂₅ phytosphingosine was the most abundant and constituted more than 50 % of all LCB.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.