ArticleThe journal of nutrition, health & aging2013
Mediterranean diet and depressive symptoms among older adults over time.
Article in The journal of nutrition, health & aging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 173 citations in OpenAlex.
- Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies.Molecular psychiatry · 2019Pooled it
- Dietary patterns and successful ageing: a systematic review.European journal of nutrition · 2016Pooled it
- Dietary patterns and the risk of depression in adults: a systematic review of observational studies.European journal of nutrition · 2014Pooled it
- A cluster randomized controlled trial of an online psychoeducational intervention for people with a family history of depression.BMC psychiatry · 2019Trial
- Trial
- Molecular Mechanisms of Accelerated Ageing in Geriatric Depression: Interplay of Telomere Attrition, Mitochondrial Dysfunction and Cellular Senescence.International journal of molecular sciences · 2026Review
- Cross-sectional association between a CLHLS-based diet quality score and screening-defined elevated depressive symptoms among Chinese older adults.Frontiers in nutrition · 2026Article
- Managing depression in the elderly: real-world clinical considerations and perspectives.International clinical psychopharmacology · 2025Article
- Identifying leading anti-inflammatory dietary determinants of depression and loneliness in older adults.Brain, behavior, & immunity - health · 2025Article
- Exploring the Relationship Between Lifestyle and Post-COVID Psychiatric Symptoms: Findings from a Brazilian Cohort.American journal of lifestyle medicine · 2025Article
- Untargeted metabolomics reveals quinic acid as the kiwifruit component that affects brain activity in mice.PloS one · 2025Article
- Animal and plant protein intake association with mental health, tryptophan metabolites pathways, and gut microbiota in healthy women: a cross-sectional study.BMC microbiology · 2024Article
- Mediterranean Diet and Ultra-Processed Food Intake in Older Australian Adults-Associations with Frailty and Cardiometabolic Conditions.Nutrients · 2024Article
- Negative Association of Lignan and Phytosterol Intake with Stress Perception during the COVID-19 Pandemic-A Polish Study on Young Adults.Nutrients · 2024Article
- The influence of lifestyle habits on levels of depression among rural middle school students in Northeastern China.Frontiers in public health · 2024Article
- Exploring the Therapeutic Potential of Gamma-Aminobutyric Acid in Stress and Depressive Disorders through the Gut-Brain Axis.Biomedicines · 2023Review
- Association of Probable Post-Traumatic Stress Disorder with Dietary Pattern and Gut Microbiome in a Cohort of Women.Nature. Mental health · 2023Article
- Mediterranean Diet Adherence and Depressive Symptoms among a Nationally Representative Sample of Pregnant Women in the United States.The Journal of nutrition · 2023Article
- Article
- The interaction between MC4R gene variant (rs17782313) and dominant dietary patterns on depression in obese and overweight women: a cross sectional study.BMC endocrine disorders · 2023Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo examine whether adherence to a Mediterranean-based dietary pattern is predictive of depressive symptoms among older adults.
designGeneralized estimating equation models were used to test the association between a Mediterranean-based dietary pattern and depressive symptoms over time. Models were adjusted for age, sex, race, education, income, widowhood, antidepressant use, total calorie intake, body mass index, smoking, alcohol consumption, number of self-reported medical conditions, cognitive function, and physical disability.
settingChicago, Illinois.
participantsCommunity-dwelling participants (n=3502) of the Chicago Health and Aging Project aged 65+ years (59% African American) who had no evidence of depression at the baseline. MEASUREMENTS: Adherence to a Mediterranean-based dietary pattern was assessed by the MedDietScore. Dietary evaluation was performed with a food frequency questionnaire at baseline and related to incident depression as measured by the presence of four or more depressive symptoms from the 10-item version of the Center for Epidemiologic Studies Depression scale.
resultsOver an average follow-up of 7.2 years, greater adherence to a Mediterranean-based diet was associated with a reduced number of newly occurring depressive symptoms (parameter estimate = -0.002, standard error = 0.001; p = 0.04). The annual rate of developing depressive symptoms was 98.6% lower among persons in the highest tertile of a Mediterranean-based dietary pattern compared with persons in the lowest tertile group.
conclusionOur results support the hypothesis that adherence to a diet comprised of vegetables, fruits, whole grains, fish, and legumes may protect against the development of depressive symptoms in older age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.