Evidence map›Paper›PMID 23636243›Full record

ArticleThrombosis and haemostasis2013

Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII.

Christopher G Skipwith, Sandra L Haberichter, Ashley Gehrand, X Long Zheng

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Thrombosis and haemostasis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christopher G Skipwith
Sandra L Haberichter
Ashley Gehrand
X Long Zheng
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Zimmerman Program for the Molecular and Clinical Biology of VWDP01HL081588 · NHLBI · VERSITI WISCONSIN, INC. · PI MONTGOMERY, ROBERT R · 2005 to 2016
$19.3M
Structural Correlates of Protease and Cofactor FunctionP01HL074124 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI KRISHNASWAMY, SRIRAM · 2003 to 2013
$17.6M
Structure and Function of ADAMTS13 MetalloproteaseR01HL079027 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI ZHENG, X. LONG · 2005 to 2009
$1.6M
Novel Therapeutics for Acquired Thrombotic Thrombocytopenic PurpuraR01HL115187 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHENG, X. LONG · 2013 to 2016
$1.6M
NHLBI NIH HHS HL074124NHLBI NIH HHS P01 HL074124NHLBI NIH HHS P01 HL081588NHLBI NIH HHS R01 HL079027NHLBI NIH HHS R01 HL115187
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ProteolysisADAM ProteinsADAMTS13 ProteinFactor VIIIHumansMutationvon Willebrand Disease, Type 2von Willebrand FactorADAM ProteinsADAMTS13 ProteinADAMTS13 protein, humanFactor VIIIvon Willebrand Factor

Identifiers

PMID23636243
PMCPMC3813456
OpenAlexW2152747138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.