ReviewEuropean journal of clinical nutrition2013
Control of protein and energy intake - brain mechanisms.
Review in European journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of high-protein diets on the cardiometabolic factors and reproductive hormones of women with polycystic ovary syndrome: a systematic review and meta-analysis.Nutrition & diabetes · 2024Pooled it
- A randomized cross-over trial to determine the effect of a protein vs. carbohydrate preload on energy balance in ad libitum settings.Nutrition journal · 2019Trial
- Domain-specific effects of hunger on attention and choice.Scientific reports · 2026Article
- Food Macronutrient Composition Influences Attentional Bias Toward Food Cues.Annals of the New York Academy of Sciences · 2026Article
- FGF21 as a mediator of adaptive changes in food intake and macronutrient preference in response to protein restriction.Neuropharmacology · 2024Review
- Dietary Crude Protein and Lysine Levels Affect Meat Quality and Myofiber Characteristic of Slow-Growing Chicken.Animals : an open access journal from MDPI · 2024Article
- Protein Appetite at the Interface between Nutrient Sensing and Physiological Homeostasis.Nutrients · 2021Review
- Clinical Evidence and Mechanisms of High-Protein Diet-Induced Weight Loss.Journal of obesity & metabolic syndrome · 2020Review
- FGF21 and the Physiological Regulation of Macronutrient Preference.Endocrinology · 2020Review
- High-protein and low-calorie diets improved the anti-aging Klotho protein in the rats' brain: the toxic role of high-fat diet.Nutrition & metabolism · 2020Article
- Article
- Homeostatic sensing of dietary protein restriction: A case for FGF21.Frontiers in neuroendocrinology · 2018Review
- Importance of Serum Amino Acid Profile for Induction of Hepatic Steatosis under Protein Malnutrition.Scientific reports · 2018Article
- Dietary Protein and Energy Balance in Relation to Obesity and Co-morbidities.Frontiers in endocrinology · 2018Review
- The Drosophila ETV5 Homologue Ets96B: Molecular Link between Obesity and Bipolar Disorder.PLoS genetics · 2016Article
- Hepatic autophagy contributes to the metabolic response to dietary protein restriction.Metabolism: clinical and experimental · 2016Article
- Central Amino Acid Sensing in the Control of Feeding Behavior.Frontiers in endocrinology · 2016Review
- Protein-dependent regulation of feeding and metabolism.Trends in endocrinology and metabolism: TEM · 2015Review
- Relative undernourishment and food insecurity associations with Plasmodium falciparum among Batwa pygmies in Uganda: evidence from a cross-sectional survey.The American journal of tropical medicine and hygiene · 2014Article
- Amino acid-dependent regulation of food intake: is protein more than the sum of its parts?The Journal of physiology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The protein content of the diet has long been investigated for its influence on food behavior. High-protein diets promote satiety and reduce calorie intake, whereas results for low-protein diets are more contradictory and less established. Protein sensing might take place in the oral cavity or in the post-oral gastrointestinal tract, where specific receptors have been found. Protein signaling to the brain may act through the vagal nerve and involve gastric hormones, such as cholecystokinin and peptide YY. Other pathways are post-absorptive signaling and the direct influence of brain levels of amino acids. High-protein diet enhances the activity of brain satiety centers, mainly the nucleus of the solitary tract and arcuate nucleus, although the activity of brain reward centers might also be modified. A better understanding of the role of both homeostatic and hedonic systems is needed to fully describe the influence of protein on food intake.
Indexed as
Identifiers
23636122What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.