ArticleMalaria journal2013
Severe Plasmodium falciparum and Plasmodium vivax malaria among adults at Kassala Hospital, eastern Sudan.
Article in Malaria journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Plasmodium vivax infection in Duffy-negative populations in Sudan: a systematic review and meta-analysis of host-parasite genetic adaptation.Malaria journal · 2026Pooled it
- Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports.BMC infectious diseases · 2020Pooled it
- Is Plasmodium vivax malaria a severe malaria?: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2014Pooled it
- Interferon-γ and Interleukin-10 Profiles Correlate with Disease Severity in Sudanese Children withJournal of clinical medicine · 2026Article
- Prevalence and associated factors of malaria among febrile patients at two sites with different transmission intensities, Northwest Ethiopia.Parasite epidemiology and control · 2025Article
- Cerebral Malaria in Adults: A Retrospective Descriptive Analysis of 80 Cases in a Tertiary Hospital in The Gambia, 2020-2023.Health science reports · 2025Article
- The most lethal human protozoan parasite is plasmodium falciparum: severe malaria-associated acute renal failure - a case report.Annals of medicine and surgery (2012) · 2024Article
- Clinical manifestations and outcomes of severe malaria in adult patients admitted to a tertiary hospital in the Gambia.Malaria journal · 2022Article
- Seasonal Profile and Five-Year Trend Analysis of Malaria Prevalence in Maygaba Health Center, Welkait District, Northwest Ethiopia.Journal of parasitology research · 2021Article
- Clinical Features and Mortality Associated with Severe Malaria in Adults in Southern Mauritania.Tropical medicine and infectious disease · 2020Article
- Clinical and epidemiological characterization of severeVirulence · 2020Article
- Plasmodium vivax cerebral malaria in an adult patient in Sudan.Malaria journal · 2019Article
- Discriminating Clinical and Biological Features in Malaria and Dengue Patients.Journal of arthropod-borne diseases · 2018Article
- Unexpected high circulation of Plasmodium vivax in asymptomatic children from Kédougou, southeastern Senegal.Malaria journal · 2017Article
- Severe vivax malaria: a prospective exploration at a tertiary healthcare centre in Southwestern India.Pathogens and global health · 2017Article
- Differentiating between dengue fever and malaria using hematological parameters in endemic areas of Thailand.Infectious diseases of poverty · 2017Article
- Complicated malaria in children and adults from three settings of the Colombian Pacific Coast: A prospective study.PloS one · 2017Article
- Key Knowledge Gaps for Plasmodium vivax Control and Elimination.The American journal of tropical medicine and hygiene · 2016Article
- Utility of nested polymerase chain reaction over the microscopy and immuno-chromatographic test in the detection of Plasmodium species and their clinical spectrum.Parasitology research · 2016Article
- Complicated malaria symptoms associated with Plasmodium vivax among patients visiting health facilities in Mendi town, Northwest Ethiopia.BMC infectious diseases · 2016Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThere have been few published reports on severe Plasmodium falciparum and Plasmodium vivax malaria among adults in Africa.
methodsClinical pattern/manifestations of severe P. falciparum and P. vivax (according to World Health Organization 2000 criteria) were described in adult patients admitted to Kassala Hospital, eastern Sudan.
resultsA total of 139 adult patients (80 males, 57.6%) with a mean (SD) age of 37.2 (1.5) years presented with severe P. falciparum (113, 81.3%) or P. vivax (26, 18.7%) malaria. Manifestations among the 139 patients included hypotension (38, 27.3%), cerebral malaria (23, 16.5%), repeated convulsions (18, 13.0%), hypoglycaemia (15, 10.8%), hyperparasitaemia (14, 10.1%), jaundice (14, 10.1%), severe anaemia (10, 7.2%), bleeding (six, 4.3%), renal impairment (one, 0.7%) and more than one criteria (27, 19.4%). While the geometric mean of the parasite count was significantly higher in patients with severe P. vivax than with severe P. falciparum malaria (5,934.2 vs 13,906.6 asexual stage parasitaemia per μL, p = 0.013), the different disease manifestations were not significantly different between patients with P. falciparum or P. vivax malaria. Three patients (2.2%) died due to severe P. falciparum malaria. One had cerebral malaria, the second had renal impairment, jaundice and hypoglycaemia, and the third had repeated convulsions and hypotension.
conclusionsSevere malaria due to P. falciparum and P. vivax malaria is an existing entity among adults in eastern Sudan. Patients with severe P. falciparum and P. vivax develop similar disease manifestations.
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