Evidence map›Paper›PMID 23634707›Full record

ArticleNano letters2013

Single ion channel recordings with CMOS-anchored lipid membranes.

Jacob K Rosenstein, Siddharth Ramakrishnan, Jared Roseman, Kenneth L Shepard

Abstract read
In one paragraph

Article in Nano letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Single-molecule bioelectronics.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacob K RosensteinDepartment of Electrical Engineering, Columbia University, New York, New York 10027, USA. Jacob_Rosenstein@brown.edu
Siddharth Ramakrishnan
Jared Roseman
Kenneth L Shepard

Funding

Integrated, multiplexed high-frequency electronic analysis of DNA in nanoporesR01HG006879 · NHGRI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SHEPARD, KENNETH L · 2012 to 2014
$1.4M
NHGRI NIH HHS R01 HG006879NHGRI NIH HHS R01-HG006879
6 · The paper itself

Abstract

We present single-ion-channel recordings performed with biomimetic lipid membranes which are directly attached to the surface of a complementary metal-oxide-semiconductor (CMOS) preamplifier chip. With this system we resolve single-channel currents from several types of bacterial ion channels, including fluctuations of a single alamethicin channel at a bandwidth of 1 MHz which represent the fastest single-ion-channel recordings reported to date. The platform is also used for high-resolution α-hemolysin nanopore recordings. These results illustrate the high signal fidelity, fine temporal resolution, small geometry, and multiplexed integration which can be achieved by leveraging integrated semiconductor platforms for advanced ion channel interfaces.

Indexed as

SemiconductorsBiomimeticsIon ChannelsLipid BilayersMetalsOxidesIon ChannelsLipid BilayersMetalsOxides

Identifiers

PMID23634707
PMCPMC3683112

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.