ArticleAnnals of medical and health sciences research2013
Prevalence and correlates of "high dose" antipsychotic prescribing: findings from a hospital audit.
Article in Annals of medical and health sciences research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antipsychotic Polypharmacy Among Patients With Schizophrenia in Africa: A Systematic Review and Meta-Analysis.The international journal of neuropsychopharmacology · 2021Pooled it
- Evaluation of prescribing patterns of sodium valproate in neurological disease patients: a quasi-experimental pretest-posttest design study.BMC health services research · 2025Trial
- Offenders and non-offenders with schizophrenia spectrum disorders: the crime-preventive potential of sufficient embedment in the mental healthcare and support system.Frontiers in psychiatry · 2023Article
- Antipsychotic drug dose in real-life settings results from a Nationwide Cohort Study.European archives of psychiatry and clinical neuroscience · 2022Article
- Correlates of high-dose antipsychotic prescription amongst outpatients with Schizophrenia in a Nigerian Hospital.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2022Article
- The Role of Five Facets of Mindfulness in a Mindfulness-Based Psychoeducation Intervention for People With Recent-Onset Psychosis on Mental and Psychosocial Health Outcomes.Frontiers in psychiatry · 2020Article
- Trends in the use of antipsychotics in the Israeli inpatient population, 2004-2013.Israel journal of health policy research · 2016Article
- Antipsychotic dosing: found in translation.Journal of psychiatry & neuroscience : JPN · 2014Review
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Authors and funding
4 authors.
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Abstract
backgroundHigh dose antipsychotic prescribing is common in psychiatric care, despite a lack of its benefit from research evidence. While several studies have explored the prevalence and factors associated with high dose antipsychotic prescribing, no such report has emanated from a developing country like Nigeria.
aimThe aims of this study were to determine the prevalence of high dose prescribing among in-patients at a tertiary psychiatric hospital and to determine the pattern of antipsychotic drugs prescribed. MATERIALS AND
methodsAn audit of in-patients at a regional tertiary psychiatric facility was carried out. We examined case notes and conducted oral interviews where necessary, on all patients receiving antipsychotics using a proforma designed for the study.
resultsThe prevalence of high dose prescribing was 38% (65/171) using a prescribed daily dose/defined daily dose ratio of 1.5. The rate of antipsychotic polypharmacy was 7% (12/171). The atypical antipsychotic, olanzapine was the most commonly prescribed antipsychotic in monotherapy. Predictors of high dose prescribing were diagnoses (P = 0.04), polypharmacy (P = 0.04), a history of previous in-patient care (P = 0.02), and use of anticholinergic drugs (P = 0.01).
conclusionsHigh dose prescribing was common among in-patients audited. Further studies are needed to examine factors that promote "high dose" prescribing.
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