ArticlePloS one2013
Characterization of sex determination and sex differentiation genes in Latimeria.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 68 citations in OpenAlex.
- Sex- and stage-dependent expression of gonadal soma-derived factor paralogues reveals functional and evolutionary divergence in European sea bass (Frontiers in endocrinology · 2026Article
- Polygenic sex determination in vertebrates - is there any such thing?Trends in genetics : TIG · 2023Review
- Sex Determination and Differentiation in Teleost: Roles of Genetics, Environment, and Brain.Biology · 2021Review
- A brief review of vertebrate sex evolution with a pledge for integrative research: towards 'Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Allelic diversification after transposable element exaptation promotedGenome research · 2021Article
- Functional Divergence of Multiple Duplicated Foxl2 Homeologs and Alleles in a Recurrent Polyploid Fish.Molecular biology and evolution · 2021Article
- Evolution, Expression, and Function of Gonadal Somatic Cell-Derived Factor.Frontiers in cell and developmental biology · 2021Review
- Comparative Genomics Studies on theFrontiers in genetics · 2020Article
- A Comparative View on Sex Differentiation and Gametogenesis Genes in Lungfish and Coelacanths.Genome biology and evolution · 2018Article
- The transcriptomic signature of different sexes in two protogynous hermaphrodites: Insights into the molecular network underlying sex phenotype in fish.Scientific reports · 2018Article
- The Gene Toolkit Implicated in Functional Sex in Sparidae Hermaphrodites: Inferences From Comparative Transcriptomics.Frontiers in genetics · 2018Article
- Article
- Gonadal soma controls ovarian follicle proliferation through Gsdf in zebrafish.Developmental dynamics : an official publication of the American Association of Anatomists · 2017Article
- Fibroblast growth factor signaling is required for early somatic gonad development in zebrafish.PLoS genetics · 2017Article
- Genetic sex determination in Astatotilapia calliptera, a prototype species for the Lake Malawi cichlid radiation.Die Naturwissenschaften · 2017Article
- Gene expression analysis at the onset of sex differentiation in turbot (Scophthalmus maximus).BMC genomics · 2015Article
- Complete depletion of primordial germ cells in an All-female fish leads to Sex-biased gene expression alteration and sterile All-male occurrence.BMC genomics · 2015Article
- Plasticity of gene-regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpators.EMBO reports · 2015Review
- Transcriptomics of two evolutionary novelties: how to make a sperm-transfer organ out of an anal fin and a sexually selected "sword" out of a caudal fin.Ecology and evolution · 2015Article
- Sequencing and De Novo Assembly of the Gonadal Transcriptome of the Endangered Chinese Sturgeon (Acipenser sinensis).PloS one · 2015Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genes involved in sex determination and differentiation have been identified in mice, humans, chickens, reptiles, amphibians and teleost fishes. However, little is known of their functional conservation, and it is unclear whether there is a common set of genes shared by all vertebrates. Coelacanths, basal Sarcopterygians and unique "living fossils", could help establish an inventory of the ancestral genes involved in these important developmental processes and provide insights into their components. In this study 33 genes from the genome of Latimeria chalumnae and from the liver and testis transcriptomes of Latimeria menadoensis, implicated in sex determination and differentiation, were identified and characterized and their expression levels measured. Interesting findings were obtained for GSDF, previously identified only in teleosts and now characterized for the first time in the sarcopterygian lineage; FGF9, which is not found in teleosts; and DMRT1, whose expression in adult gonads has recently been related to maintenance of sexual identity. The gene repertoire and testis-specific gene expression documented in coelacanths demonstrate a greater similarity to modern fishes and point to unexpected changes in the gene regulatory network governing sexual development.
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