Evidence map›Paper›PMID 23633754›Full record

ArticleSleep2013

Sleep disordered breathing and gestational hypertension: postpartum follow-up study.

John Reid, Riley A Glew, Robert Skomro, Mark Fenton, David Cotton, Femi Olatunbosun, John Gjevre, Christian Guilleminault

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Sleep, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02755831 (Randomized Controlled Trial for a Sleep Study and Targeted CPAP Therapy for Obstructive Sleep Apnea to Reduce the Incidence Adverse Pregnancy Related Outcomes), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02755831 nacompletednot on this mapstarted 2017, after this paper: background citation

Randomized Controlled Trial for a Sleep Study and Targeted CPAP Therapy for Obstructive Sleep Apnea to Reduce the Incidence Adverse Pregnancy Related Outcomes

TypeinterventionalSponsorUnited States Naval Medical Center, San DiegoRan2017 to 2019Enrolled193ConditionsObstructive Sleep ApneaArmsCPAP, Pre-natal care
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  5. Obstructive sleep apnea in pregnant women.International anesthesiology clinics · 2022
    Article
  6. Review
  7. Review
  8. Management of Obstructive Sleep Apnea in Pregnancy.Obstetrics and gynecology clinics of North America · 2018
    Review
  9. Sleep disordered breathing in pregnancy.Breathe (Sheffield, England) · 2015
    Review
  10. Secondary Hypertension in Pregnancy.Current hypertension reports · 2015
    Review
  11. Hypertension, snoring, and obstructive sleep apnoea during pregnancy: a cohort study.BJOG : an international journal of obstetrics and gynaecology · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

John ReidDivision of Respiratory Medicine, University of Saskatchewan, Saskatoon, SK Canada. j.reid@usask.ca
Riley A Glew
Robert Skomro
Mark Fenton
David Cotton
Femi Olatunbosun
John Gjevre
Christian Guilleminault
University of Saskatchewan · CAPalo Alto University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational hypertension (GH) is a newly recognized risk factor for adverse cardiovascular events later in life. Sleep disordered breathing (SDB) is an established risk factor for adverse cardiovascular events. Recent research has suggested that women with GH may have an increased rate of SDB during pregnancy, but it is not known if this higher rate of SDB persists into the postpartum state.

objectiveTo assess whether women with GH continue to have an increased rate of SDB compared to healthy pregnant women, after the physiologic changes of pregnancy resolve.

methodsWe previously studied women with GH and uncomplicated pregnancies with sleep questionnaires and level 1 polysomnography. Participants were invited to participate in repeat testing 1-2 years postpartum. Respiratory disturbance index (RDI) differences were assessed.

resultsEighteen subjects (11 GH and 7 healthy) had complete follow-up data available for comparison with antepartum data. This group was representative of the initial antepartum cohort. Women with GH experienced a decrease in mean RDI from antepartum to postpartum (12.0 ± 12.3 vs. 2.9 ± 2.9; P = 0.02). Healthy women did not experience the same change (2.8 ± 5.3 vs. 2.1 ± 3.2; P = 0.81). Postpartum comparisons showed the mean RDI of women with GH had decreased to be similar to that of healthy women (P = 0.75).

conclusionsSDB in women with gestational hypertension improved in the postpartum state to levels indistinguishable from our healthy subjects. This suggests that the physiologic effects of pregnancy may have had a pathologic role in the development of antepartum SDB in women with GH.

Indexed as

AdultBody Mass IndexCase-Control StudiesFemaleFollow-Up StudiesHumansHypertension, Pregnancy-InducedPolysomnographyPregnancyPuerperal DisordersRisk FactorsSleep Apnea SyndromesSurveys and QuestionnairesYoung AdultGestational hypertensionpostpartumpreeclampsiasleep disordered breathing

Identifiers

PMID23633754
PMCPMC3624826
OpenAlexW1986702385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.