Evidence map›Paper›PMID 23633672›Full record

ArticleGut microbes

Mechanisms and consequence of bacteria detection by the Drosophila gut epithelium.

Julien Royet, Bernard Charroux

Abstract readComment
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Julien RoyetAix-Marseille Université, CNRS, Institut de Biologie du Développement de Marseille-Luminy UMR CNRS 7288, Marseille, France. julien.royet@univ-amu.fr
Bernard Charroux

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since insect mostly developed on decaying matter and contaminated fruits, they are constantly ingesting bacteria. The insect model, Drosophila, is therefore well adapted to study the interactions that take place between the gut epithelia and either resident or infectious bacteria. In order to provide an ad hoc immune response, gut epithelial cells must detect the presence of bacteria. In a recent report, Bosco-Drayon et al. identify the main receptors by which Drosophila sense gut associated bacteria and analyze how this bacteria-receptor interaction translate into gene activation.

Indexed as

Biological EvolutionMating Preference, AnimalMetagenomeSymbiosisAnimalsBacteriaDrosophila melanogasterFemaleGastrointestinal TractHumansMaledrosophilagut epitheliamicrobiotaNF-kBpeptidoglycanPGRP

Identifiers

PMID23633672
PMCPMC3669173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.