ReviewUrolithiasis2013
The genetic composition of Oxalobacter formigenes and its relationship to colonization and calcium oxalate stone disease.
Review in Urolithiasis, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 67 citations in OpenAlex.
- Association between high fat diet and kidney stones based on the National Health and Nutrition Examination Survey (NHANES) 2007-2020: a cross-sectional study.Translational andrology and urology · 2025Article
- Engineered microorganisms: A new direction in kidney stone prevention and treatment.Synthetic and systems biotechnology · 2024Review
- Purslane-induced oxalate nephropathy: case report and literature review.BMC nephrology · 2023Review
- Kidney Stone Prevention: Is There a Role for Complementary and Alternative Medicine?Nutrients · 2023Review
- Oxalate as a potent promoter of kidney stone formation.Frontiers in medicine · 2023Review
- Probiotic Oxalate-Degrading Bacteria: New Insight of Environmental Variables and Expression of the oxc and frc Genes on Oxalate Degradation Activity.Foods (Basel, Switzerland) · 2022Review
- An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria.Molecular systems biology · 2022Article
- Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist.Applied and environmental microbiology · 2021Review
- Recent advances on the mechanisms of kidney stone formation (Review).International journal of molecular medicine · 2021Review
- Genetic Background but Not Intestinal Microbiota After Co-Housing Determines Hyperoxaluria-Related Nephrocalcinosis in Common Inbred Mouse Strains.Frontiers in immunology · 2021Article
- Gut microbiota affect the formation of calcium oxalate renal calculi caused by high daily tea consumption.Applied microbiology and biotechnology · 2021Article
- Contribution of Dietary Oxalate and Oxalate Precursors to Urinary Oxalate Excretion.Nutrients · 2020Review
- Interactions Between Phytochemicals and Minerals inFrontiers in nutrition · 2020Article
- Development of a Humanized Murine Model for the Study of Oxalobacter formigenes Intestinal Colonization.The Journal of infectious diseases · 2019Article
- Immunity, microbiota and kidney disease.Nature reviews. Nephrology · 2019Review
- The Role of the Genitourinary Microbiome in Pediatric Urology: a Review.Current urology reports · 2018Review
- Oxalobacter formigenes-associated host features and microbial community structures examined using the American Gut Project.Microbiome · 2017Article
- Screening of Oxalate Degrading Lactic Acid Bacteria of Food Origin.Italian journal of food safety · 2017Article
- The role of intestinal oxalate transport in hyperoxaluria and the formation of kidney stones in animals and man.Urolithiasis · 2017Review
- Microbiome in the urinary system-a review.AIMS microbiology · 2017Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Oxalobacter formigenes is a unique intestinal organism that relies on oxalate degradation to meet most of its energy and carbon needs. A lack of colonization is a risk factor for calcium oxalate stone disease. Protection against calcium oxalate stone disease appears to be due to the oxalate degradation that occurs in the gut on low calcium diets with a possible further contribution from intestinal oxalate secretion. Much remains to be learned about how the organism establishes and maintains gut colonization and the precise mechanisms by which it modifies stone risk. The sequencing and annotation of the genomes of a Group 1 and a Group 2 strain of O. formigenes should provide the informatic tools required for the identification of the genes and pathways associated with colonization and survival. In this review we have identified genes that may be involved and where appropriate suggested how they may be important in calcium oxalate stone disease. Elaborating the functional roles of these genes should accelerate our understanding of the organism and clarify its role in preventing stone formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.