Trial reportInternational urogynecology journal2013
The use of transvaginal synthetic mesh for anterior vaginal wall prolapse repair: a randomized controlled trial.
Trial report in International urogynecology journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 7 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Transvaginal mesh or grafts or native tissue repair for vaginal prolapse.The Cochrane database of systematic reviews · 2024Pooled it
- Is levator ani avulsion a risk factor for prolapse recurrence? A systematic review and meta-analysis.International urogynecology journal · 2022Pooled it
- A systematic review of outcome and outcome-measure reporting in randomised trials evaluating surgical interventions for anterior-compartment vaginal prolapse: a call to action to develop a core outcome set.International urogynecology journal · 2018Pooled it
- Anterior colporrhaphy: a standard operation? Systematic review of the technical aspects of a common procedure in randomized controlled trials.International urogynecology journal · 2018Pooled it
- Surgery for women with anterior compartment prolapse.The Cochrane database of systematic reviews · 2016Pooled it
- Mesh Surgery for Anterior Vaginal Wall Prolapse: A Meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2016Pooled it
- Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse.The Cochrane database of systematic reviews · 2016Pooled it
- A randomized controlled trial comparing anatomical and functional outcome between vaginal colposuspension and transvaginal mesh.International urogynecology journal · 2014Trial
- Outcomes and patient satisfaction after pelvic organ prolapse surgery with and without mesh: a retrospective cohort study with prospective follow-up.Archives of gynecology and obstetrics · 2026Article
- Quality of Life Assessment After Pelvic Prolapse Surgery With and Without Mesh: A Literature Review.Journal of clinical medicine · 2025Review
- Mesh-augmented transvaginal repair of recurrent or complex anterior pelvic organ prolapse in accordance with the SCENIHR opinion.International urogynecology journal · 2021Article
- Current surgical management of pelvic organ prolapse: Strategies for the improvement of surgical outcomes.Investigative and clinical urology · 2019Review
- Managing female pelvic floor disorders: a medical device review and appraisal.Interface focus · 2019Review
- Diagnosis and Therapy of Female Pelvic Organ Prolapse. Guideline of the DGGG, SGGG and OEGGG (S2e-Level, AWMF Registry Number 015/006, April 2016).Geburtshilfe und Frauenheilkunde · 2016Article
- The treatment of anterior vaginal wall prolapsed by repair with mesh versus colporrhaphy.International urology and nephrology · 2016Review
- Vaginal Approaches Using Synthetic Mesh to Treat Pelvic Organ Prolapse.Annals of coloproctology · 2016Review
- Comparison of location of mesh placed transvaginally vs mesh placed abdominally at the time of sacrocolpopexy.International urogynecology journal · 2015Article
- Management of pelvic organ prolapse.Korean journal of urology · 2014Review
- Anterior colporrhaphy: why surgeon performance is paramount.International urogynecology journal · 2014Article
- Device Selection Contributes to Operative Time Reduction in Laparoscopic Sacrocolpopexy.Gynecology and minimally invasive therapyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe aim of the study was to compare the efficacy and safety of transvaginal trocar-guided polypropylene mesh insertion with traditional colporrhaphy for treatment of anterior vaginal wall prolapse.
methodsThis is a randomized controlled trial in which women with advanced anterior vaginal wall prolapse, at least stage II with Ba ≥ +1 cm according to the Pelvic Organ Prolapse Quantification (POP-Q) classification, were randomly assigned to have either anterior colporrhaphy (n = 39) or repair using trocar-guided transvaginal mesh (n = 40). The primary outcome was objective cure rate of the anterior compartment (point Ba) assessed at the 12-month follow-up visit, with stages 0 and I defined as anatomical success. Secondary outcomes included quantification of other vaginal compartments (POP-Q points), comparison of quality of life by the prolapse quality of life (P-QOL) questionnaire, and complication rate between the groups after 1 year. Study power was fixed as 80% with 5% cutoff point (p < 0.05) for statistical significance.
resultsThe groups were similar regarding demographic and clinical preoperative parameters. Anatomical success rates for colporrhaphy and repair with mesh placement groups were 56.4 vs 82.5% (95% confidence interval 0.068-0.54), respectively, and the difference between the groups was statistically significant (p = 0.018). Similar total complication rates were observed in both groups, with tape exposure observed in 5% of the patients. There was a significant improvement in all P-QOL domains as a result of both procedures (p < 0.001), but they were not distinct between groups (p > 0.05).
conclusionsTrocar-guided transvaginal synthetic mesh for advanced anterior POP repair is associated with a higher anatomical success rate for the anterior compartment compared with traditional colporrhaphy. Quality of life equally improved after both techniques. However, the trial failed to detect differences in P-QOL scores and complication rates between the groups.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.