ReviewEuropean journal of human genetics : EJHG2013
Controlling complexity: the clinical relevance of mouse complex genetics.
Review in European journal of human genetics : EJHG, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- The human neuropsychiatric risk gene Drd2 is necessary for social functioning across evolutionary distant species.Molecular psychiatry · 2024Article
- Knockout mouse models as a resource for the study of rare diseases.Mammalian genome : official journal of the International Mammalian Genome Society · 2023Article
- Evolutionary rewiring of regulatory networks contributes to phenotypic differences between human and mouse orthologous genes.Nucleic acids research · 2022Article
- Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry.Nature neuroscience · 2019Article
- Putative human sperm Interactome: a networks study.BMC systems biology · 2018Article
- Article
- Application of Mouse Models to Research in Hearing and Balance.Journal of the Association for Research in Otolaryngology : JARO · 2016Review
- INFRAFRONTIER: a European resource for studying the functional basis of human disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2016Review
- Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.BMC genomics · 2016Article
- Mouse Genetic Models of Human Brain Disorders.Frontiers in genetics · 2016Review
- Host genetic diversity influences the severity of Pseudomonas aeruginosa pneumonia in the Collaborative Cross mice.BMC genetics · 2015Article
- Contrasting genetic architectures in different mouse reference populations used for studying complex traits.Genome research · 2015Review
- INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community.Nucleic acids research · 2015Article
- The genetic basis for susceptibility to Rift Valley fever disease in MBT/Pas mice.Genes and immunityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Experimental animal models are essential to obtain basic knowledge of the underlying biological mechanisms in human diseases. Here, we review major contributions to biomedical research and discoveries that were obtained in the mouse model by using forward genetics approaches and that provided key insights into the biology of human diseases and paved the way for the development of novel therapeutic approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.