ArticleIntensive care medicine2013
Early diffusion-weighted magnetic resonance imaging in children after cardiac arrest may provide valuable prognostic information on clinical outcome.
Article in Intensive care medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- 2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 8. Pediatric advanced life support.Clinical and experimental emergency medicine · 2026Guideline
- Predictive values of early head computed tomography for survival outcome after cardiac arrest in childhood: a pilot study.Scientific reports · 2021Trial
- Brain MR imaging and spectroscopy for outcome prognostication after pediatric cardiac arrest.Resuscitation · 2020Trial
- Continuation or Withdrawal of Life-sustaining Therapies After Acute Anoxic Events in Childhood and Adolescence : Can Early MRI Predict Particularly Severe Outcomes?Clinical neuroradiology · 2026Article
- Severe intracranial hemorrhage or ischemia associated with unfavorable outcomes after pediatric in-hospital cardiac arrest.Resuscitation · 2026Article
- Long-term multidisciplinary follow-up programs in pediatric cardiac arrest survivors.Resuscitation plus · 2024Article
- Neuromonitoring after Pediatric Cardiac Arrest: Cerebral Physiology and Injury Stratification.Neurocritical care · 2024Review
- Assessment of Brain Magnetic Resonance and Spectroscopy Imaging Findings and Outcomes After Pediatric Cardiac Arrest.JAMA network open · 2023Article
- Magnetic resonance imaging adds prognostic value to EEG after pediatric cardiac arrest.Resuscitation · 2022Observational
- Parenchymal brain injuries in abusive head trauma.Pediatric radiology · 2021Review
- Association of MRI Brain Injury With Outcome After Pediatric Out-of-Hospital Cardiac Arrest.Neurology · 2021Article
- Neurological Prognostication in Children After Cardiac Arrest.Pediatric neurology · 2020Review
- How can neurological outcomes be predicted in comatose pediatric patients after out-of-hospital cardiac arrest?Clinical and experimental pediatrics · 2020Article
- Neurologic Outcomes Following Care in the Pediatric Intensive Care Unit.Current treatment options in pediatrics · 2017Article
- Early prognostication markers in cardiac arrest patients treated with hypothermia.European journal of neurology · 2016Review
- Long-term neuropsychological outcomes in children and adolescents after cardiac arrest.Intensive care medicine · 2015Article
- Comparison of transcranial ultrasound and cranial MRI in evaluations of brain injuries from neonatal asphyxia.International journal of clinical and experimental medicine · 2015Article
- Year in review in Intensive Care Medicine 2013: III. Sepsis, infections, respiratory diseases, pediatrics.Intensive care medicine · 2014Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe examined whether early diffusion-weighted magnetic resonance imaging (DW-MRI) abnormalities of the brain and variation of apparent diffusion coefficient (ADC) values can provide prognostic information on clinical outcome in children following cardiac arrest (CA).
designRetrospective study.
settingA 12-bed paediatric intensive care unit (PICU). PATIENTS: Children aged between 1 month and 18 years who had DW-MRI with ADC measurement within the first week following CA. Neurological outcomes were assessed using the Pediatric Cerebral Performance Category Scale (PCPC). Differences between the favourable (PCPC ≤3) and unfavourable (PCPC ≥4) groups were analysed with regard to clinical data, electrophysiological patterns as well as qualitative and quantitative DW-MRI abnormalities.
resultsTwenty children with a median age of 20 months (1.5-185) and a male/female sex ratio of 1.5 underwent DW-MRI after CA with a median delay of 3 days (1-7). Aetiologies of CA were (i) asphyxia (n = 10), (ii) haemodynamic (n = 5) or (iii) unknown (n = 5). With regard to DW-MRI findings, the unfavourable outcome group (n = 8) was associated with cerebral cortex (p = 0.02) and basal ganglia (p = 0.005) lesions, with a larger number of injured brain regions (p = 0.001) and a global decrease in measured ADC signal (p = 0.008). Normal DW-MRI (n = 5) was exclusively associated with the favourable outcome group (n = 12).
conclusionQualitative, topographic and quantitative analysis of early DW-MRI with ADC measurement in children following CA may provide valuable prognostic information on neurological outcomes.
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