ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2013
Arrested growth and spontaneous tumor regression of partially resected low-grade cerebellar astrocytomas in children.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Dynamic Tumor Volume Changes after Debulking Surgery of Optic Hypothalamus Pilocytic Astrocytoma.Neurologia medico-chirurgica · 2026Article
- Spontaneous regression of epileptogenic pilocytic astrocytoma with FGFR1-TACC1 fusion.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Imaging of brain tumors in children: the basics-a narrative review.Translational pediatrics · 2021Review
- From astrocytoma to glioblastoma: a clonal evolution study.FEBS open bio · 2020Article
- Clonal pattern dynamics in tumor: the concept of cancer stem cells.Scientific reports · 2019Article
- Twenty-three years follow-up after low-dose Gamma Knife surgery of a brainstem juvenile pilocytic astrocytoma: a case report and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Review
- Spontaneous Slowing and Regressing of Tumor Growth in Childhood/Adolescent Papillary Thyroid Carcinomas Suggested by the Postoperative Thyroglobulin-Doubling Time.Journal of thyroid research · 2018Article
- Mortality in children with low-grade glioma or glioneuronal tumors: A single-institution study.Pediatric blood & cancer · 2018Article
- MR imaging of brain pilocytic astrocytoma: beyond the stereotype of benign astrocytoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Review
- Vanishing pineal mass in a young patient without therapy: Case report and review of the literature.The neuroradiology journal · 2016Review
- Model-Based Evaluation of Spontaneous Tumor Regression in Pilocytic Astrocytoma.PLoS computational biology · 2015Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe prognosis of children with low-grade cerebellar astrocytoma who have partial resection of tumor is largely unpredictable. The purpose of this study was to review the long-term outcome of such patients.
methodsThe medical charts, imaging findings, operative notes, histopathological reports, and survival times of 12 patients with cerebellar astrocytoma were reviewed.
resultsFive patients had total resection and seven had partial resection. Nine patients had grade I histology and three patients had grade II. Follow-up duration ranged from 3 to 25 years. Among the seven patients with residual tumor, five had tumor progression, one had arrested tumor growth, and one had spontaneous tumor regression. Five patients with partial resection received radiotherapy and three had malignant transformation of tumor during follow-up. Six patients, including five who had partial resection, underwent a second operation. One patient with partial resection died of pneumonia 23 years after surgery.
conclusionsPatients with complete tumor resection had a better prognosis than patients with partial resection. For patients with partial resection, we recommend a "wait and see" policy with surveillance using MRI. The phenomenon of arrested tumor growth and spontaneous tumor regression in patients with cerebellar astrocytoma who have subtotal resection warrants further study.
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