ArticleOphthalmology2013
The economic burden of vision loss and eye disorders among the United States population younger than 40 years.
Article in Ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02909985 (Visual Activity Evoked by Infrared in Humans After Dark Adaptation), which is not on this map. Cited by 76 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Visual Activity Evoked by Infrared in Humans After Dark Adaptation
Who cites it
76 citing papers in PubMed, 2 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- Evaluating Large Language Models in Ophthalmology: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Evaluating the Quantity and Quality of Health Economic Literature in Blinding Childhood Disorders: A Systematic Literature Review.PharmacoEconomics · 2024Pooled it
- Article
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- A holistic approach for quantifying the value of public health programs: social return on investment (SROI) analysis of a mobile clinic as an example.Frontiers in public health · 2026Article
- ROQUS: a retinal OCT quality and usability score.Biomedical optics express · 2025Article
- Anomaly Detection in Retinal OCT Images With Deep Learning-Based Knowledge Distillation.Translational vision science & technology · 2025Article
- Assessing the Diagnostic Capabilities of ChatGPT-4 Omni in Grading Diabetic Retinopathy Fundoscopy Using Color Fundus Photographs.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- A mobile system for whole eye perfusion supporting retinal function and surgery.Frontiers in bioengineering and biotechnology · 2025Article
- Emerging Therapeutic Approaches and Genetic Insights in Stargardt Disease: A Comprehensive Review.International journal of molecular sciences · 2024Review
- The societal economic impact of vision impairment in adults 40 years and above: findings from the National Eye Survey of Trinidad and Tobago.Eye (London, England) · 2024Article
- Stargardt macular dystrophy and therapeutic approaches.The British journal of ophthalmology · 2024Review
- Real-World Healthcare Resource Utilization, Healthcare Costs, and Injurious Falls Among Elderly Patients with Geographic Atrophy.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- A deep-learning pipeline for the diagnosis and grading of common blinding ophthalmic diseases based on lesion-focused classification model.Frontiers in artificial intelligence · 2024Article
- Evaluating the network adequacy of vision care services for children in Arizona: A cross sectional study.AIMS public health · 2024Article
- Group-Based Trajectory Analysis of Longitudinal Employment Patterns and Predictors for Adults With Visual Impairments.Journal of vocational rehabilitation · 2024Article
- EFFECTIVENESS OF TEACHERS IN THE DETECTION OF EYE DISORDERS AMONG PRIMARY SCHOOL CHILDREN IN ABAKALIKI METROPOLIS, EBONYI STATE NIGERIA.Annals of Ibadan postgraduate medicine · 2023Article
- Economic Burden of Vision Loss and Eye Disorders in Iran.Iranian journal of public health · 2023Article
- Re-hospitalizations within 30-days and mortality outcomes among severely visually impaired and blind patients: analysis of the National Readmission Database.BMC ophthalmology · 2023Article
- The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies.Cellular and molecular life sciences : CMLS · 2023Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo estimate the economic burden of vision loss and eye disorders in the United States population younger than 40 years in 2012.
designEconometric and statistical analysis of survey, commercial claims, and census data.
participantsThe United States population younger than 40 years in 2012.
methodsWe categorized costs based on consensus guidelines. We estimated medical costs attributable to diagnosed eye-related disorders, undiagnosed vision loss, and medical vision aids using Medical Expenditure Panel Survey and MarketScan data. The prevalence of vision impairment and blindness were estimated using National Health and Nutrition Examination Survey data. We estimated costs from lost productivity using Survey of Income and Program Participation. We estimated costs of informal care, low vision aids, special education, school screening, government spending, and transfer payments based on published estimates and federal budgets. We estimated quality-adjusted life years (QALYs) lost based on published utility values.
main outcome measuresCosts and QALYs lost in 2012.
resultsThe economic burden of vision loss and eye disorders among the United States population younger than 40 years was $27.5 billion in 2012 (95% confidence interval, $21.5-$37.2 billion), including $5.9 billion for children and $21.6 billion for adults 18 to 39 years of age. Direct costs were $14.5 billion, including $7.3 billion in medical costs for diagnosed disorders, $4.9 billion in refraction correction, $0.5 billion in medical costs for undiagnosed vision loss, and $1.8 billion in other direct costs. Indirect costs were $13 billion, primarily because of $12.2 billion in productivity losses. In addition, vision loss cost society 215 000 QALYs.
conclusionsWe found a substantial burden resulting from vision loss and eye disorders in the United States population younger than 40 years, a population excluded from previous studies. Monetizing quality-of-life losses at $50 000 per QALY would add $10.8 billion in additional costs, indicating a total economic burden of $38.2 billion. Relative to previously reported estimates for the population 40 years of age and older, more than one third of the total cost of vision loss and eye disorders may be incurred by persons younger than 40 years. FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.