ReviewBiomedical engineering online2013
Neurovascular coupling: in vivo optical techniques for functional brain imaging.
Review in Biomedical engineering online, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 123 citations in OpenAlex.
- The relationship between motor and cognitive performance and cortical activity in patients with multiple sclerosis: a systematic review of functional near-infrared spectroscopy studies.Frontiers in rehabilitation sciences · 2026Pooled it
- Escaping through virtual gaming-what is the association with emotional, social, and mental health? A systematic review.Frontiers in psychiatry · 2023Pooled it
- Relationship between motor performance and cortical activity of older neurological disorder patients with dyskinesia using fNIRS: A systematic review.Frontiers in physiology · 2023Pooled it
- Functional near-infrared spectroscopy: Systematic mapping of abnormal brain function features in neurological disorders.Neural regeneration research · 2026Article
- Frontotemporal cortical activity in Chinese male alcohol-dependent patients during a verbal fluency task: a functional near-infrared spectroscopy study.Frontiers in psychiatry · 2026Article
- Neurovascular Coupling: Scientometric Analysis of 30 Years Research (1996-2025).Brain and behavior · 2025Article
- Revolutionizing cross professional collaboration outcomes in TBI: emerging trends in diagnostics, personalized medicine, technological innovations and neurorehabilitation.Brain informatics · 2025Review
- The non-invasive transcranial Doppler for hemodynamic monitoring.Physiological research · 2025Article
- Wide-Based Illumination and Detection in Functional Near-Infrared Spectroscopy for Enhanced Seizure Detection in Grey Matter.Sensors (Basel, Switzerland) · 2025Article
- Induction of haemodynamic travelling waves by glial-related vasomotion in a rat model of neuroinflammation: implications for functional neuroimaging.EBioMedicine · 2025Article
- Simultaneous head-mounted imaging of neural and hemodynamic activities at high spatiotemporal resolution in freely behaving mice.Science advances · 2025Article
- Cerebral hemodynamics and functional connectivity changes in stroke patients with dysphagia under acidic taste stimulation: a preliminary study.Frontiers in neurology · 2025Article
- Article
- Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus.Talanta · 2024Article
- Technology of the photobiostimulation of the brain's drainage system during sleep for improvement of learning and memory in male mice.Biomedical optics express · 2024Article
- Detection of low-frequency oscillations in neonatal piglets with speckle contrast diffuse correlation tomography.Journal of biomedical optics · 2023Article
- Assessing depth sensitivity in laser interferometry speckle visibility spectroscopy (iSVS) through source-to-detector distance variation and cerebral blood flow monitoring in humans and rabbits.Biomedical optics express · 2023Article
- Article
- Word Structure Tunes Electrophysiological and Hemodynamic Responses in the Frontal Cortex.Bioengineering (Basel, Switzerland) · 2023Article
- Amyloid Deposition and Dendritic Complexity of Corticocortical Projection Cells in Five Familial Alzheimer's Disease Mouse.Neuroscience · 2023Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 3 countries.
Funding
Abstract
Optical imaging techniques reflect different biochemical processes in the brain, which is closely related with neural activity. Scientists and clinicians employ a variety of optical imaging technologies to visualize and study the relationship between neurons, glial cells and blood vessels. In this paper, we present an overview of the current optical approaches used for the in vivo imaging of neurovascular coupling events in small animal models. These techniques include 2-photon microscopy, laser speckle contrast imaging (LSCI), voltage-sensitive dye imaging (VSDi), functional photoacoustic microscopy (fPAM), functional near-infrared spectroscopy imaging (fNIRS) and multimodal imaging techniques. The basic principles of each technique are described in detail, followed by examples of current applications from cutting-edge studies of cerebral neurovascular coupling functions and metabolic. Moreover, we provide a glimpse of the possible ways in which these techniques might be translated to human studies for clinical investigations of pathophysiology and disease. In vivo optical imaging techniques continue to expand and evolve, allowing us to discover fundamental basis of neurovascular coupling roles in cerebral physiology and pathophysiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.