ArticleOrphanet journal of rare diseases2013
Clinicopathological study of glomerular diseases associated with sarcoidosis: a multicenter study.
Article in Orphanet journal of rare diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2020Guideline
- Secondary Membranous Nephropathy. A Narrative Review.Frontiers in medicine · 2020Pooled it
- Kidney outcomes and prognostic factors in biopsy-proven kidney sarcoidosis: a nationwide multicenter cohort study.Clinical kidney journal · 2026Article
- Kidneys in the crossfire: insights into renal sarcoidosis.BMC nephrology · 2026Observational
- Case Report: Renal sarcoidosis coexisting with membranous and IgA nephropathy, a very uncommon association.Frontiers in nephrology · 2026Article
- Isolated renal sarcoidosis and concurrent secondary membranous nephropathy: a case report.Journal of medical case reports · 2025Article
- Antigens in membranous nephropathy: discovery and clinical implications.Nature reviews. Nephrology · 2025Review
- Epidemiological study of renal involvement in sarcoidosis in Japan using the Japan Renal Biopsy Registry.Clinical and experimental nephrology · 2025Article
- Therapeutic Challenges and New Era in Fibrillary Glomerulonephritis with the Introduction of DNAJB9: Experience from a Tertiary Nephrology Center.Journal of clinical medicine · 2025Article
- Rapidly progressive glomerulonephritis as an unusual type of renal involvement in sarcoidosis: a case report.Journal of medical case reports · 2025Article
- Renal sarcoidosis: renal pathology guides diagnosis and prognosis.Diagnostic pathology · 2024Article
- Review
- The co-occurrence of sarcoidosis and anti-PLA2R-associated membranous nephropathy in a patient with underlying genetic susceptibility.BMC nephrology · 2024Article
- High-Risk Sarcoidosis: A Focus on Pulmonary, Cardiac, Hepatic and Renal Advanced Diseases, as Well as on Calcium Metabolism Abnormalities.Diagnostics (Basel, Switzerland) · 2024Review
- Clinicopathological features for the prediction of immunosuppressive treatment responses in sarcoidosis-related kidney involvement: a single-center retrospective study.Turkish journal of medical sciences · 2024Article
- Systemic sarcoidosis presenting as a rare combination of interstitial nephritis with necrotizing vasculitis and urinary retention due to prostate involvement: a case report.BMC nephrology · 2023Article
- Heterogeneity of Target Antigens in Sarcoidosis-Associated Membranous Nephropathy.Kidney international reports · 2023Article
- A case of systemic sarcoidosis with mesangial proliferative glomerulonephritis showing predominant deposition of IgG in the mesangial region.CEN case reports · 2022Article
- Renal replacement therapy in sarcoidosis.Frontiers in medicine · 2022Review
- Sarcoidosis-associated renal AA amyloidosis and crescentic necrotizing glomerulonephritis.Proceedings (Baylor University. Medical Center) · 2022Article
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Authors and funding
17 authors at 6 institutions in 1 country.
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Abstract
backgroundThe association between sarcoidosis and glomerular diseases has not been extensively investigated in a large series and the potential features of this uncommon association remain to be determined.
methodsWe retrospectively identified 26 patients with biopsy-proven glomerular lesions that occurred in a sarcoidosis context. Potential remission of glomerular disease and sarcoidosis under specific treatment (steroid and/or immunosuppressive agents) was recorded for all patients. Demographic, clinical and biological characteristics were assessed at the time of kidney biopsy for each patient. Therapeutic data were analyzed for all patients.
resultsGlomerular disease occurred after the diagnosis of sarcoidosis in 11 of 26 cases (42%) (mean delay of 9.7 years). In six patients (23%), the glomerulopathy preceded the sarcoidosis diagnosis (mean delay 8 years). In the last nine patients (35%), both conditions occurred simultaneously. The most frequent glomerular disease occurring in sarcoidosis patients was membranous nephropathy in eleven cases. Other glomerular lesions included IgA nephropathy in six cases, focal segmental glomerulosclerosis in four patients, minimal change nephrotic syndrome for three patients and proliferative lupus nephritis in two patients. Granulomatous interstitial nephritis was associated with glomerular disease in six patients and was exclusively found in patients in whom the both disease occurred simultaneously. In nine patients with simultaneous glomerular and sarcoidosis diseases, we observed a strong dissociation between glomerular disease and sarcoidosis in terms of steroid responsiveness. At the end of the follow-up (mean of 8.4 years), six patients had reached end-stage renal disease and three patients had died.
conclusionsA wide spectrum of glomerular lesions is associated with sarcoidosis. The close temporal relationship observed in some patients suggests common causative molecular mechanisms of glomerular injury but complete remission of both diseases in response to exclusive steroid therapy is infrequent.
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