Evidence map›Paper›PMID 23630456›Full record

ArticlePLoS biology2013

Subgrouping the autism "spectrum": reflections on DSM-5.

Meng-Chuan Lai, Michael V Lombardo, Bhismadev Chakrabarti, Simon Baron-Cohen

Abstract read
In one paragraph

Article in PLoS biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A Conceptual Framework for Understanding the Cultural and Contextual Factors on Autism Across the Globe.Autism research : official journal of the International Society for Autism Research · 2020
    Pooled it
  5. Trial
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  9. Article
  10. Higher Intraindividual Gait Variability in Autistic Toddlers: A Pilot Study.Journal of autism and developmental disorders · 2025
    Article
  11. Spanish Validation of the Autism Spectrum Quotient for Children (AQ-Child-SV).Journal of autism and developmental disorders · 2025
    Article
  12. A Frank Assessment of SHANK: Impacts of Pathogenic Variations in SHANK3 on Preclinical Models of Phelan McDermid Syndrome.Autism research : official journal of the International Society for Autism Research · 2025
    Review
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Meng-Chuan LaiAutism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK. mcl45@cam.ac.uk
Michael V Lombardo
Bhismadev Chakrabarti
Simon Baron-Cohen

Funding

Medical Research Council G0600977Medical Research Council G1100359Wellcome Trust
6 · The paper itself

Abstract

DSM-5 has moved autism from the level of subgroups ("apples and oranges") to the prototypical level ("fruit"). But making progress in research, and ultimately improving clinical practice, will require identifying subgroups within the autism spectrum.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersChildChild Development Disorders, PervasiveHumansSeverity of Illness Index

Identifiers

PMID23630456
PMCPMC3635864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.