Evidence map›Paper›PMID 23630416›Full record

ArticlePatient preference and adherence2013

Evaluation of preference for a novel durable insulin pen with memory function among patients with diabetes and health care professionals.

Gerhard Klausmann, Irene Hramiak, Marianne Qvist, Kristian Handberg Mikkelsen, Xiaohui Guo

Registry-linked trialAbstract read
In one paragraph

Article in Patient preference and adherence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04847778 (Randomized Clinical Trial to Assess the Efficacy of the System Insulclock® 360 for Insulin Treatment Management in Type 1 Diabetes Patients With Insufficient Glycemic Control), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04847778 nacompletednot on this mapstarted 2021, after this paper: background citation

Randomized Clinical Trial to Assess the Efficacy of the System Insulclock® 360 for Insulin Treatment Management in Type 1 Diabetes Patients With Insufficient Glycemic Control

TypeinterventionalSponsorHospital General de SegoviaRan2021 to 2021Enrolled80ConditionsDiabetes Mellitus, Type 1ArmsUse of Insulclock system, both Insulclock device and Insulclock 360 app., Use of Insulclock system, both Insulclock device and Insulclock app on masked mode.
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Digital Diabetes Management: A Literature Review of Smart Insulin Pens.Journal of diabetes science and technology · 2022
    Review
  5. Article
  6. Patient Perceptions and Preferences for a Mealtime Insulin Delivery Patch.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2018
    Article
  7. Review
  8. Biosimilar insulins: a European perspective.Diabetes, obesity & metabolism · 2015
    Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gerhard KlausmannInternal Medicine Diabetology Practice, Aschaffenburg, Germany.
Irene Hramiak
Marianne Qvist
Kristian Handberg Mikkelsen
Xiaohui Guo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImproving adherence to insulin treatment for better glycemic control remains a challenge in the management of diabetes. New technological aids are required to help support adherence. This study evaluated preference for the NovoPen(®) 5 (NP5), a durable insulin pen with memory function, compared with the HumaPen Luxura(®) (HPL) among patients with diabetes and health care professionals.

methodsThis crossover, multicenter usability study included insulin pen-experienced patients with diabetes and health care professionals treating patients with diabetes in Canada, China, and Germany. Participants evaluated NP5 and HPL in a randomized order by performing handling tasks in a usability test related to everyday use during a face-to-face interview. Tasks, pens, and preferences were assessed by completing a questionnaire comprised of rating and open-ended questions relating to confidence in everyday diabetes management.

resultsOverall, 300 patients with diabetes and 150 health care professionals participated in the study. Significantly more participants preferred NP5 (81%) to HPL (18%) (P < 0.001). Also, 82% of patients with diabetes had more confidence in NP5 for managing their daily injections versus 11% with HPL (P < 0.001), and 7% had no preference. Memory function was most helpful in giving patients with diabetes confidence about when they last injected (63%), how much insulin they last injected (62%) and improving diabetes management (55%). Participants gave higher ratings to NP5 than to HPL on all parameters relating to performing an injection (ease of handling, satisfaction when using the pen, convenience of using the pen day-to-day, quality of the pen, and the extent to which the pen meets their needs; P < 0.05 for all comparisons).

conclusionNP5 was preferred to HPL by most participants. Significantly more patients with diabetes had more confidence for managing daily insulin injections when using NP5, the pen with a memory function.

Indexed as

confidencediabetesdurable insulin penmemory functionpatient preferenceusability

Identifiers

PMID23630416
PMCPMC3623548

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.