Trial reportCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2013
Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial.
Trial report in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 48 citations in OpenAlex.
- A naturopathic approach to the prevention of cardiovascular disease: cost-effectiveness analysis of a pragmatic multi-worksite randomized clinical trial.Journal of occupational and environmental medicine · 2014Trial
- Investigating the Epigenetic Therapeutic Potential of Natural Compounds in Cancer.International journal of molecular sciences · 2025Review
- Assessing the Feasibility of Rural Residency Training for Licensed Naturopathic Physicians in the Northwest: A Qualitative Study.Integrative medicine reports · 2023Article
- Naturopathic Doctors: An Underutilized Resource of Whole Health Delivery in Primary Care.Global advances in health and medicine · 2022Article
- Overview of international naturopathic practice and patient characteristics: results from a cross-sectional study in 14 countries.BMC complementary medicine and therapies · 2020Article
- Naturopathy as a Model of Prevention-Oriented, Patient-Centered Primary Care: A Disruptive Innovation in Health Care.Medicina (Kaunas, Lithuania) · 2019Article
- A Hierarchy of Healing: Origins of the Therapeutic Order and Implications for Research.Integrative medicine (Encinitas, Calif.) · 2019Article
- Whole Systems Research Methods in Health Care: A Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019Article
- Lessons from Outside and Within: Exploring Advancements in Methodology for Naturopathic Medicine Clinical Research.Journal of alternative and complementary medicine (New York, N.Y.) · 2019Article
- The State of the Evidence for Whole-System, Multi-Modality Naturopathic Medicine: A Systematic Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019Article
- Naturopathic medicine for preventing cardiovascular disease.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016Article
- Variation among cardiovascular risk calculators in relative risk increases with identical risk factor increases.BMC research notes · 2015Article
- The characteristics, experiences and perceptions of naturopathic and herbal medicine practitioners: results from a national survey in New Zealand.BMC complementary and alternative medicine · 2015Article
- Complementary medical health services: a cross sectional descriptive analysis of a Canadian naturopathic teaching clinic.BMC complementary and alternative medicine · 2015Article
- Institute for Integrative Health in $1-Million Grant to Explore Nature's Effect on Wounded Warriors … plus more.Integrative medicine (Encinitas, Calif.) · 2014Article
- Advising on diet and lifestyle: naturopathy's role?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Advising on diet and lifestyle: naturopathy's role?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Advising on diet and lifestyle: naturopathy's role?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Advising on diet and lifestyle: naturopathy's role?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Can naturopaths deliver complementary preventive medicine?CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
- Commented on by
- Commented on by
- Erratum issued
Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough cardiovascular disease may be partially preventable through dietary and lifestyle-based interventions, few individuals at risk receive intensive dietary and lifestyle counselling. We performed a randomized controlled trial to evaluate the effectiveness of naturopathic care in reducing the risk of cardiovascular disease.
methodsWe performed a multisite randomized controlled trial of enhanced usual care (usual care plus biometric measurement; control) compared with enhanced usual care plus naturopathic care (hereafter called naturopathic care). Postal workers aged 25-65 years in Toronto, Vancouver and Edmonton, Canada, with an increased risk of cardiovascular disease were invited to participate. Participants in both groups received care by their family physicians. Those in the naturopathic group also received individualized care (health promotion counselling, nutritional medicine or dietary supplementation) at 7 preset times in work-site clinics by licensed naturopathic doctors. The body weight, waist circumference, lipid profile, fasting glucose levels and blood pressure of participants in both groups were measured 3 times during a 1-year period. Our primary outcomes were the 10-year risk of having a cardiovascular event (based on the Framingham risk algorithm) and the prevalence of metabolic syndrome (based on the Adult Treatment Panel III diagnostic criteria).
resultsOf 246 participants randomly assigned to a study group, 207 completed the study. The characteristics of participants in both groups were similar at baseline. Compared with participants in the control group, at 52 weeks those in the naturopathic group had a reduced adjusted 10-year cardiovascular risk (control: 10.81%; naturopathic group: 7.74%; risk reduction -3.07% [95% confidence interval (CI) -4.35% to -1.78%], p < 0.001) and a lower adjusted frequency of metabolic syndrome (control group: 48.48%; naturopathic care: 31.58%; risk reduction -16.90% [95% CI -29.55% to -4.25%], p = 0.002).
interpretationOur findings support the hypothesis that the addition of naturopathic care to enhanced usual care may reduce the risk of cardiovascular disease among those at high risk.
trial registrationClinicalTrials.gov, no. NCT0071879.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.