ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2013
Bone and skeletal muscle: neighbors with close ties.
Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 192 citations in OpenAlex.
- Weighted Vest Use or Resistance Exercise to Offset Weight Loss-Associated Bone Loss in Older Adults: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Effect of 12-weeks elastic band resistance training on MyomiRs and osteoporosis markers in elderly women with Osteosarcopenic obesity: a randomized controlled trial.BMC geriatrics · 2021Trial
- Trial
- High doses of vitamin C plus E reduce strength training-induced improvements in areal bone mineral density in elderly men.European journal of applied physiology · 2017Trial
- Observational
- Risk factors for abnormal bone mineral density in Duchenne muscular dystrophy and the association of regular rehabilitation with bone health.Frontiers in pediatrics · 2026Article
- Slo1 Deficient Myoblast Exosomes-Derived miR-222-3p Inhibits Osteogenic Differentiation via Targeting of STAT3.Journal of cachexia, sarcopenia and muscle · 2025Article
- Determinants of Bone Mineral Density in Postmenopausal Women: The Role of Lean and Fat Mass by Dual Energy X-Ray Absorptiometry Assessment.Journal of bone metabolism · 2025Article
- Grazing-Induced Changes in circRNAs, miRNAs and mRNAs Expression in Tibetan Sheep Biceps Femoris.Biology · 2025Article
- Parathyroid Hormone as a Modulator of Skeletal Muscle: Insights into Bone-Muscle and Nerve-Muscle Interactions.International journal of molecular sciences · 2025Review
- Exploration of Crucial miRNA Signatures and Molecular Mechanisms in the System of Muscle-Exosome-Bone: Evidence from Transcriptome Data.ACS omega · 2025Article
- Tripartite motif-containing 27 negatively regulates NF-κB activation in bone remodeling.Molecular medicine (Cambridge, Mass.) · 2025Article
- Numerical study of interstitial fluid flow behavior in osteons under dynamic loading.BMC musculoskeletal disorders · 2025Article
- The beneficial effects of a probiotic mix on bone and lean mass are dependent on the diet in female mice.Scientific reports · 2025Article
- Evaluation of using grip strength and hand muscle cross-sectional area to predict secondary fractures post distal radius fracture.Archives of osteoporosis · 2025Article
- The role of bone-derived factors in bone and muscle communication.Frontiers in endocrinology · 2025Review
- Radiological frontiers in understanding paraspinal muscle pathophysiology in chronic low back pain.Frontiers in medicine · 2025Review
- Utilizing physical educators to monitor muscular strength and neuromuscular control among children with varied recess time.Frontiers in sports and active living · 2025Article
- Bone biomarkers in post-polio clinic patients.Frontiers in endocrinology · 2025Article
- Treatment with PB125Annals of biomedical engineering · 2024Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
The musculoskeletal system evolved in mammals to perform diverse functions that include locomotion, facilitating breathing, protecting internal organs, and coordinating global energy expenditure. Bone and skeletal muscles involved with locomotion are both derived from somitic mesoderm and accumulate peak tissue mass synchronously, according to genetic information and environmental stimuli. Aging results in the progressive and parallel loss of bone (osteopenia) and skeletal muscle (sarcopenia) with profound consequences for quality of life. Age-associated sarcopenia results in reduced endurance, poor balance, and reduced mobility that predispose elderly individuals to falls, which more frequently result in fracture because of concomitant osteoporosis. Thus, a better understanding of the mechanisms underlying the parallel development and involution of these tissues is critical to developing new and more effective means to combat osteoporosis and sarcopenia in our increasingly aged population. This perspective highlights recent advances in our understanding of mechanisms coupling bone and skeletal muscle mass, and identify critical areas where further work is needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.