ArticleAngewandte Chemie (International ed. in English)2013
A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of nonnatural reaction.
Article in Angewandte Chemie (International ed. in English), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed.
- How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution.Chemical Society reviews · 2026Review
- Fishing for Catalysis: Experimental Approaches to Narrowing Search Space in Directed Evolution of Enzymes.JACS Au · 2023Review
- NMR-guided directed evolution.Nature · 2022Article
- Rational design of allosteric switchable catalysts.Exploration (Beijing, China) · 2022Review
- Acyl Transfer Catalytic Activity in De Novo Designed Protein with N-Terminus of α-Helix As Oxyanion-Binding Site.Journal of the American Chemical Society · 2021Article
- MinimalistACS catalysis · 2019Article
- Article
- A Designed Enzyme Promotes Selective Post-translational Acylation.Chembiochem : a European journal of chemical biology · 2018Article
- Exploring the Development of Ground-State Destabilization and Transition-State Stabilization in Two Directed Evolution Paths of Kemp Eliminases.ACS catalysis · 2017Article
- A redox-mediated Kemp eliminase.Nature communications · 2017Article
- Kemp Eliminase Activity of Ketosteroid Isomerase.Biochemistry · 2017Article
- Design of Catalytic Peptides and Proteins Through Rational and Combinatorial Approaches.Annual review of biomedical engineering · 2016Review
- Computational strategies for the design of new enzymatic functions.Archives of biochemistry and biophysics · 2015Review
- Design of an allosterically regulated retroaldolase.Protein science : a publication of the Protein Society · 2015Article
- Intrinsically disordered caldesmon binds calmodulin via the "buttons on a string" mechanism.PeerJ · 2015Article
- Catalytic efficiency of designed catalytic proteins.Current opinion in structural biology · 2014Review
- Design of catalytically amplified sensors for small molecules.Biomolecules · 2014Review
- Experimental evolution of a green fluorescent protein composed of 19 unique amino acids without tryptophan.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2014Article
- Reprogramming EF-hands for design of catalytically amplified lanthanide sensors.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2013Article
Corrections and comments
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Authors and funding
11 authors.
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.