Evidence map›Paper›PMID 23629608›Full record

ArticlePediatrics2013

Medication errors in the home: a multisite study of children with cancer.

Kathleen E Walsh, Douglas W Roblin, Saul N Weingart, Kathleen E Houlahan, Barbara Degar, Amy Billett, Christopher Keuker, Colleen Biggins, Justin Li, Karen Wasilewski and 1 more

Registry-linked trialOpen access · bronzeAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04150120 (eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness - Development, Evaluation and Implementation in Clinical Practice), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04150120 nacompletednot on this mapstarted 2019, after this paper: background citation

eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness - Development, Evaluation and Implementation in Clinical Practice

TypeinterventionalSponsorLund UniversityRan2019 to 2025Enrolled720ConditionsPreterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital MalformationArmse-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application, Self-care for children with intravenous treatment at home
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Parental involvement in paediatric patient safety incidents in general practice: a cross-sectional study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  7. Article
  8. Review
  9. Novel Use of a Simulation in Pediatric Type 1 Diabetes Sick-Day Education for Patients and Caregivers.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Improved home management of oral pediatric anticancer drugs as a result of an intervention comprising practical training, written instructions and movie clips: A pilot study.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2023
    Article
  17. Home Cancer Care Research: A Bibliometric and Visualization Analysis (1990-2021).International journal of environmental research and public health · 2022
    Article
  18. Article
  19. Patient Safety in Ambulatory Pediatrics.Current treatment options in pediatrics · 2020
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Kathleen E WalshDepartments of Pediatrics, University of Massachusetts School of Medicine, Worcester, MA 01655, USA. walshk02@ummhc.org
Douglas W Roblin
Saul N Weingart
Kathleen E Houlahan
Barbara Degar
Amy Billett
Christopher Keuker
Colleen Biggins
Justin Li
Karen Wasilewski
Kathleen M Mazor
Dana-Farber Cancer Institute · USBoston Children's Museum · USPediatrics and Genetics · USEmory and Henry College · USKaiser Permanente · USUniversity of Massachusetts Chan Medical School · US

Funding

The HMO Cancer Research Network (CRN)U19CA079689 · NCI · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI WAGNER, EDWARD H · 1999 to 2011
$62.6M
NCI NIH HHS U19 CA079689NCI NIH HHS U19 CA 79689
6 · The paper itself

Abstract

objectiveAs home medication use increases, medications previously managed by nurses are now managed by patients and their families. Our objective was to describe the types of errors occurring in the home medication management of children with cancer.

methodsIn a prospective observational study at 3 pediatric oncology clinics in the northeastern and southeastern United States, patients undergoing chemotherapy and their parents were recruited from November 2007 through April 2011. We reviewed medical records and checked prescription doses. A trained nurse visited the home, reviewed medication bottles, and observed administration. Two physicians independently made judgments regarding whether an error occurred and its severity. Overall rates of errors were weighted to account for clustering within sites.

resultsWe reviewed 963 medications and observed 242 medication administrations in the homes of 92 patients. We found 72 medication errors. Four errors led to significant patient injury. An additional 40 errors had potential for injury: 2 were life-threatening, 13 were serious, and 25 were significant. Error rates varied between study sites (40-121 errors per 100 patients); the weighted overall rate was 70.2 errors per 100 patients (95% confidence interval [CI]: 58.9-81.6). The weighted rate of errors with injury was 3.6 (95% CI: 1.7-5.5) per 100 patients and with potential to injure the patient was 36.3 (95% CI: 29.3-43.3) per 100 patients. Nonchemotherapy medications were more often involved in an error than chemotherapy.

conclusionsMedication errors were common in this multisite study of outpatient pediatric cancer care. Rates of preventable medication-related injuries in this outpatient population were comparable or higher than those found in studies of hospitalized patients.

Indexed as

Community Health NursingDrug MonitoringHome NursingAdolescentAmbulatory CareAntineoplastic Combined Chemotherapy ProtocolsCancer Care FacilitiesChildChild, PreschoolCohort StudiesConfidence IntervalsDrug Administration ScheduleFemaleHumansIncidenceMaleantineoplastic agentsmedical errorsmedication errorspatient safetypediatric cancerquality improvement

Identifiers

PMID23629608
PMCPMC4074655
OpenAlexW2125221948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.