Evidence map›Paper›PMID 23628872›Full record

ArticleBiomatter

Adipose and mammary epithelial tissue engineering.

Wenting Zhu, Celeste M Nelson

Open access · bronzeAbstract read
In one paragraph

Article in Biomatter. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Tissue engineering and regenerative medicine strategies for the female breast.Journal of tissue engineering and regenerative medicine · 2020
    Review
  4. Frontiers in Oncologic Reconstruction.Plastic and reconstructive surgery. Global open · 2019
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wenting ZhuDepartment of Chemical and Biological Engineering; Princeton University; Princeton, NJ USA.
Celeste M NelsonDepartment of Chemical and Biological Engineering; Princeton University; Princeton, NJ USA; Department of Molecular Biology; Princeton University; Princeton, NJ USA.
Princeton University · US

Funding

Spatial patterning of branching morphogenesisR01GM083997 · NIGMS · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2008 to 2012
$1.4M
Mechanical regulation of branching morphogenesisR21HL110335 · NHLBI · PRINCETON UNIVERSITY · PI NELSON, CELESTE M · 2011 to 2012
$443k
NHLBI NIH HHS HL110335NHLBI NIH HHS R21 HL110335NIGMS NIH HHS GM083997NIGMS NIH HHS R01 GM083997
6 · The paper itself

Abstract

Breast reconstruction is a type of surgery for women who have had a mastectomy, and involves using autologous tissue or prosthetic material to construct a natural-looking breast. Adipose tissue is the major contributor to the volume of the breast, whereas epithelial cells comprise the functional unit of the mammary gland. Adipose-derived stem cells (ASCs) can differentiate into both adipocytes and epithelial cells and can be acquired from autologous sources. ASCs are therefore an attractive candidate for clinical applications to repair or regenerate the breast. Here we review the current state of adipose tissue engineering methods, including the biomaterials used for adipose tissue engineering and the application of these techniques for mammary epithelial tissue engineering. Adipose tissue engineering combined with microfabrication approaches to engineer the epithelium represents a promising avenue to replicate the native structure of the breast.

Indexed as

Epithelial-Mesenchymal TransitionTissue EngineeringAdipocytesAdipose TissueBiomedical EngineeringEpithelial CellsFemaleHumansMammary Glands, HumanStem Cells3Dmammary epitheliummorphogenesisorganotypicpatterning

Identifiers

PMID23628872
PMCPMC3749276
OpenAlexW2053058393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.