ArticlePediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2013
The ideal time interval for critical care severity-of-illness assessment.
Article in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Plasma Linoleic Acid Is Associated With Pediatric Sepsis Phenotype and Acute Kidney Injury.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026Article
- Clinical Characteristics and Outcomes of Pediatric Oncology Patients Admitted to the Pediatric Intensive Care Unit: A Single Center Experience in Saudi Arabia.Children (Basel, Switzerland) · 2025Article
- Continuous Hemodynamic Response to Angiotensin II in Critically Ill Pediatric Patients: A Single Center Cohort Study.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025Article
- Intravenous Sodium Ferric Gluconate Complex for Hospitalized Pediatric Patients with Iron Deficiency Anemia.Children (Basel, Switzerland) · 2025Article
- Ceftazidime-Avibactam Use in a Case Series of Difficult-to-Treat or Recurrent Infections in Pediatric Patients with Complex Chronic Conditions: Effectiveness and Absence of Resistance Development.Antibiotics (Basel, Switzerland) · 2024Article
- Comparison of Scoring Systems for Mortality Prediction in Pediatric Multitrauma Patients.Journal of pediatric intensive care · 2024Article
- Predicting functional and quality-of-life outcomes following pediatric sepsis: performance of PRISM-III and PELOD-2.Pediatric research · 2023Article
- Mortality Risk Factors in Pediatric Onco-Critical Care Patients and Machine Learning Derived Early Onco-Critical Care Phenotypes in a Retrospective Cohort.Critical care explorations · 2023Article
- [Analysis of ROX Index, ROX-HR Index, and SpOJournal of Korean Academy of Nursing · 2023Article
- Multisystem Inflammatory Syndrome in Children Admitted to a Tertiary Pediatric Intensive Care Unit.Journal of pediatric intensive care · 2023Article
- Parent post-traumatic growth after a child's critical illness.Frontiers in pediatrics · 2022Article
- Pediatric interfacility transport effects on mortality and length of stay.World journal of pediatrics : WJP · 2021Article
- Implementation of Multimodality Neurologic Monitoring Reporting in Pediatric Traumatic Brain Injury Management.Neurocritical care · 2021Article
- Predicting cardiac arrests in pediatric intensive care units.Resuscitation · 2018Article
- PICU Length of Stay: Factors Associated With Bed Utilization and Development of a Benchmarking Model.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2018Article
- Morbidity and mortality prediction in pediatric heart surgery: Physiological profiles and surgical complexity.The Journal of thoracic and cardiovascular surgery · 2017Article
- Limiting and Withdrawing Life Support in the PICU: For Whom Are These Options Discussed?Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Article
- The Pediatric Risk of Mortality Score: Update 2015.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2016Article
- Simultaneous Prediction of New Morbidity, Mortality, and Survival Without New Morbidity From Pediatric Intensive Care: A New Paradigm for Outcomes Assessment.Critical care medicine · 2015Article
- Red Blood Cell Distribution Width as a Pragmatic Marker for Outcome in Pediatric Critical Illness.PloS one · 2015Article
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Authors and funding
16 authors.
Funding
Abstract
objectiveDetermine if the shortest sampling interval for laboratory variables used to estimate baseline severity of illness in pediatric critical care is equivalently sensitive across multiple sites without site-specific bias, while accounting for the vast majority of dysfunction compared with the standard 0- to 12-hour Pediatric Risk of Mortality III score.
designProspective random patient selection.
settingGeneral/medical and cardiac/cardiovascular PICUs in eight hospitals. PATIENTS: Patients younger than 18 years admitted to the PICU.
interventionsNone. MEASUREMENTS AND MAIN
resultsA total of 376 patients were included. Measurements for Pediatric Risk of Mortality III laboratory variables (pH, PCO2, total CO2, PaO2, glucose, potassium, blood urea nitrogen, creatinine, total WBC count, platelet count, and prothrombin time/partial thromboplastin time) were recorded from 2 hours prior to PICU admission through 12 hours of PICU care except for data in the operating room. Decreasing the observation period from 0 to 12 hours post-PICU admission resulted in progressive decreases in the Pediatric Risk of Mortality III laboratory variables measured. However, allowing the observation period to start 2 hours prior to PICU admission to 4 hours reduced this loss to only 3.4%. Similar trends existed for each of the individual laboratory Pediatric Risk of Mortality III variables. There was a nearly identical distribution of laboratory Pediatric Risk of Mortality III points within the -2- to 4-hour period compared with the standard period. We did not detect any institutional bias using the -2- to 4-hour time period compared with the baseline.
conclusionsPrognostically important laboratory physiologic data collected within the interval from 2 hours prior to PICU to admission through 4 hours after admission account for the vast majority of dysfunction that these variables would contribute to Pediatric Risk of Mortality III scores. There was no institutional bias associated with this sampling period.
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