ReviewNeuroscience and biobehavioral reviews2013
Recovering from cocaine: insights from clinical and preclinical investigations.
Review in Neuroscience and biobehavioral reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Distinct patterns of prefrontal cortical disengagement during inhibitory control in addiction: A meta-analysis based on population characteristics.Neuroscience and biobehavioral reviews · 2021Pooled it
- Cocaine-specific speed-accuracy trade-off during anti-saccade testing differentiates patients with cocaine use disorder who achieve initial abstinence during treatment.Journal of psychopharmacology (Oxford, England) · 2021Trial
- Alexithymia, Reward Sensitivity and Internet Addiction Symptoms: Potential Roles of Frontal Lobe Dysfunction and Negative Mood.International journal of psychology : Journal international de psychologie · 2025Article
- Astrocytic transcriptional and epigenetic mechanisms of drug addiction.Journal of neural transmission (Vienna, Austria : 1996) · 2024Review
- Prelimbic cortex and nucleus accumbens core resting state signaling dynamics as a biomarker for cocaine seeking behaviors.Addiction neuroscience · 2023Article
- Residual deficits in functional brain activity after chronic cocaine self-administration in rhesus monkeys.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Impaired verbal memory in individuals living with HIV and cocaine dependence.Journal of clinical and experimental neuropsychology · 2022Article
- Single Low Dose of Cocaine-Structural Brain Injury Without Metabolic and Behavioral Changes.Frontiers in neuroscience · 2020Article
- State-Dependent Effects of Ventromedial Prefrontal Cortex Continuous Thetaburst Stimulation on Cocaine Cue Reactivity in Chronic Cocaine Users.Frontiers in psychiatry · 2019Article
- Transdiagnostic Effects of Ventromedial Prefrontal Cortex Transcranial Magnetic Stimulation on Cue Reactivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Modulating Neural Circuits with Transcranial Magnetic Stimulation: Implications for Addiction Treatment Development.Pharmacological reviews · 2018Review
- Dose response of acute cocaine on sleep/waking behavior in mice.Neurobiology of sleep and circadian rhythms · 2018Article
- Toward biomarkers of the addicted human brain: Using neuroimaging to predict relapse and sustained abstinence in substance use disorder.Progress in neuro-psychopharmacology & biological psychiatry · 2018Review
- Commentary on Schmitz et al. (2017): Advancing medication development for addiction-behavioral and neuroimaging outcomes as indirect biomarkers of target engagement.Addiction (Abingdon, England) · 2017Article
- Longitudinal Changes in Brain Metabolic Activity after Withdrawal from Escalation of Cocaine Self-Administration.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Article
- Neurofunctional Reward Processing Changes in Cocaine Dependence During Recovery.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Article
- Synaptic mechanisms underlying persistent cocaine craving.Nature reviews. Neuroscience · 2016Review
- Long-Term Blockade of Cocaine Self-Administration and Locomotor Activation in Rats by an Adenoviral Vector-Delivered Cocaine Hydrolase.The Journal of pharmacology and experimental therapeutics · 2016Article
- Biomarkers for Success: Using Neuroimaging to Predict Relapse and Develop Brain Stimulation Treatments for Cocaine-Dependent Individuals.International review of neurobiology · 2016Review
- Altered white matter in cocaine-dependent subjects with traumatic brain injury: A diffusion tensor imaging study.Drug and alcohol dependence · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cocaine remains one of the most addictive substances of abuse and one of the most difficult to treat. Although increasingly sophisticated experimental and technologic advancements in the last several decades have yielded a large body of clinical and preclinical knowledge on the direct effects of cocaine on the brain, we still have a relatively incomplete understanding of the neurobiological processes that occur when drug use is discontinued. The goal of this manuscript is to review both clinical and preclinical data related to abstinence from cocaine and discuss the complementary conclusions that emerge from these different levels of inquiry. This commentary will address observed alterations in neural function, neural structure, and neurotransmitter system regulation that are present in both animal models of cocaine abstinence and data from recovering clinical populations. Although these different levels of inquiry are often challenging to integrate, emerging data discussed in this commentary suggest that from a structural and functional perspective, the preservation of cortical function that is perhaps the most important biomarker associated with extended abstinence from cocaine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.