Evidence map›Paper›PMID 23628376›Full record

ArticleEmerging infectious diseases2013

Description and nomenclature of Neisseria meningitidis capsule locus.

Odile B Harrison, Heike Claus, Ying Jiang, Julia S Bennett, Holly B Bratcher, Keith A Jolley, Craig Corton, Rory Care, Jan T Poolman, Wendell D Zollinger and 9 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 178 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 1 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

178 citing papers in PubMed, 1 synthesis or guideline pooled it, 312 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Molecular characterization of Neisseria meningitidis isolates from healthy individuals in Meigu County, Sichuan Province, 2021-2024.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  10. Rapid and recent evolution ofMicrobial genomics · 2026
    Article
  11. Article
  12. Genomic characterization of invasiveEmerging microbes & infections · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

118 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 4 countries.

Odile B HarrisonDepartment of Zoology, University of Oxford, Oxford, UK. odile.harrison@zoo.ox.ac.uk
Heike Claus
Ying Jiang
Julia S Bennett
Holly B Bratcher
Keith A Jolley
Craig Corton
Rory Care
Jan T Poolman
Wendell D Zollinger
Carl E Frasch
David S Stephens
Ian Feavers
Matthias Frosch
Julian Parkhill
Ulrich Vogel
Michael A Quail
Stephen D Bentley
Martin C J Maiden
University of Würzburg · DEUniversity of Oxford · GBWalter Reed Army Institute of Research · USEmory University · USJohnson & Johnson (Netherlands) · NLNational Institute for Biological Standards and Control · GBWellcome Sanger Institute · GB

Funding

Wellcome Trust 087622
6 · The paper itself

Abstract

Pathogenic Neisseria meningitidis isolates contain a polysaccharide capsule that is the main virulence determinant for this bacterium. Thirteen capsular polysaccharides have been described, and nuclear magnetic resonance spectroscopy has enabled determination of the structure of capsular polysaccharides responsible for serogroup specificity. Molecular mechanisms involved in N. meningitidis capsule biosynthesis have also been identified, and genes involved in this process and in cell surface translocation are clustered at a single chromosomal locus termed cps. The use of multiple names for some of the genes involved in capsule synthesis, combined with the need for rapid diagnosis of serogroups commonly associated with invasive meningococcal disease, prompted a requirement for a consistent approach to the nomenclature of capsule genes. In this report, a comprehensive description of all N. meningitidis serogroups is provided, along with a proposed nomenclature, which was presented at the 2012 XVIIIth International Pathogenic Neisseria Conference.

Indexed as

Chromosomes, BacterialGenes, BacterialBacterial CapsulesGenetic LociHumansMagnetic Resonance SpectroscopyMeningococcal InfectionsMultigene FamilyNeisseria meningitidisPolymerase Chain ReactionPolysaccharides, BacterialSerotypingTerminology as TopicVirulencePolysaccharides, BacterialbacteriacapsuleNeisseria meningitidisnomenclatureserogroup

Identifiers

PMID23628376
PMCPMC3647402
OpenAlexW2005977813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.