ReviewCurrent opinion in structural biology2013
Molecular mechanism of the Escherichia coli maltose transporter.
Review in Current opinion in structural biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 100 citations in OpenAlex.
- Molecular mechanism of phosphate import by the bacterial PstSCAB transporter.Nature communications · 2026Article
- DeFrND: detergent-free reconstitution into native nanodiscs with designer membrane scaffold peptides.Nature communications · 2025Article
- Structurally diverse C-terminal accessory domains in type I ABC importers reveal distinct regulatory mechanisms.Structure (London, England : 1993) · 2025Review
- An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality.Nature structural & molecular biology · 2024Article
- Biosensor that Detects Stress Caused by Periplasmic Proteins.ACS synthetic biology · 2024Article
- The substrate-binding domains of the osmoregulatory ABC importer OpuA transiently interact.eLife · 2024Article
- Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.Nature plants · 2023Article
- Molecular recognition of trehalose and trehalose analogues byProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Structural basis for negative regulation of the Escherichia coli maltose system.Nature communications · 2023Article
- Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB.Protein & cell · 2023Article
- Article
- Assembly and Maintenance of Lipids at the Bacterial Outer Membrane.Chemical reviews · 2021Review
- Developing Nanodisc-ID for label-free characterizations of membrane proteins.Communications biology · 2021Article
- Structures of ABC transporters: handle with care.FEBS letters · 2020Review
- If you eat it, or secrete it, they will grow: the expanding list of nutrients utilized by human gut bacteria.Journal of bacteriology · 2020Review
- Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.Science advances · 2020Article
- Transporters of glucose and other carbohydrates in bacteria.Pflugers Archiv : European journal of physiology · 2020Review
- Passenger sequences can promote interlaced dimers in a common variant of the maltose-binding protein.Scientific reports · 2019Article
- The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters.Structure (London, England : 1993) · 2019Article
- Evidence from Mutational Analysis for a Single Transmembrane Substrate Binding Site in the Histidine ATP-Binding Cassette Transporter of Salmonella enterica Serovar Typhimurium.Journal of bacteriology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
ATP-binding cassette (ABC) transporters are ubiquitous membrane proteins that import and export a large variety of materials across the lipid bilayer. A key question that drives ABC transporter research is how ATP hydrolysis is coupled to substrate translocation. This review uses the maltose transporter of Escherichia coli as a model system to understand the molecular mechanism of ABC importers. X-ray crystallography was used to capture the structures of the maltose transporter in multiple conformations. These structures, interpreted in the light of functional data, are discussed to address the following questions: first, what is the nature of conformational changes in a transport cycle? Second, how does substrate activate ATPase activity? Third, how does ATP hydrolysis enable substrate transport?
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.