Evidence map›Paper›PMID 23626922›Full record

ArticleJournal of data mining in genomics & proteomics2012

From the Large Scale Expression Analysis of Lupus Nephritis to Targeted Molecular Medicine.

Celine C Berthier, Matthias Kretzler, Anne Davidson

Open access · hybridAbstract read
In one paragraph

Article in Journal of data mining in genomics & proteomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Urinary biomarkers in lupus nephritis.Journal of translational autoimmunity · 2020
    Review
  5. A systems approach to renal inflammation in SLE.Clinical immunology (Orlando, Fla.) · 2017
    Review
  6. An update on lupus animal models.Current opinion in rheumatology · 2017
    Review
  7. Article
  8. What is damaging the kidney in lupus nephritis?Nature reviews. Rheumatology · 2016
    Review
  9. Article
  10. Lupus nephritis: review of the literature.Current allergy and asthma reports · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Celine C BerthierDepartment of Internal Medicine, Nephrology, University of Michigan, Ann Arbor, MI 48109, USA.
Matthias Kretzler
Anne Davidson
University of Michigan–Ann Arbor · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
University of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 2008 to 2022
$12.9M
Targeting renal inflammatory pathways of SLE nephritis in mouse and manR01DK085241 · NIDDK · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DAVIDSON, ANNE · 2010 to 2013
$2.2M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK081943NIDDK NIH HHS R01 DK085241
6 · The paper itself

Abstract

Lupus nephritis (LN) is one of the most severe complications of systemic lupus erythematosus (SLE). Current treatments for LN lack sufficient efficacy as they do not necessarily target the LN responsible pathways and therapeutic responses vary widely in the patient population. LN mouse models have been useful in delineating disease pathogenesis and for testing novel therapies, but they do not entirely represent the events happening in human LN. This review describes how recently developed systems biology technologies can help to integrate current knowledge with large scale experimental data to generate new hypotheses and insight into the regulatory events occurring in LN.

Indexed as

HumanMouse modelsNephritisSLESystems biology

Identifiers

PMID23626922
PMCPMC3634599
OpenAlexW2027538703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.