ArticleJournal of clinical neurology (Seoul, Korea)2013
Cortico-cortical modulation induced by 1-Hz repetitive transcranial magnetic stimulation of the temporal cortex.
Article in Journal of clinical neurology (Seoul, Korea), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Changing Cerebral Blood Flow, Glucose Metabolism, and Dopamine Binding Through Transcranial Magnetic Stimulation: A Systematic Review of Transcranial Magnetic Stimulation-Positron Emission Tomography Literature.Pharmacological reviews · 2022Pooled it
- Effects of Noninvasive Brain Stimulation Combined With Antidepressants in Patients With Poststroke Depression: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2022Pooled it
- Therapeutic impact of repetitive transcranial magnetic stimulation (rTMS) on tinnitus: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Pooled it
- Changes in motor cortex excitability associated with temporal repetitive transcranial magnetic stimulation in tinnitus: hints for cross-modal plasticity?BMC neuroscience · 2014Trial
- Single-day accelerated TMS with D-cycloserine augmentation for depression: A placebo-controlled trial.Research square · 2025Article
- The potential application of electrophysiological indicators in TMS treatment for MOH.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- Functional Activity in the Effect of Transcranial Magnetic Stimulation Therapy for Patients with Depression: A Meta-Analysis.Journal of personalized medicine · 2023Review
- Insight Into the Effects of Clinical Repetitive Transcranial Magnetic Stimulation on the Brain From Positron Emission Tomography and Magnetic Resonance Imaging Studies: A Narrative Review.Frontiers in neuroscience · 2022Review
- Low-frequency electrical stimulation reduces cortical excitability in the human brain.NeuroImage. Clinical · 2021Article
- Acupuncture Treatment Decreased Temporal Variability of Dynamic Functional Connectivity in Chronic Tinnitus.Frontiers in neuroscience · 2021Article
- Neural metabolic activity in idiopathic tinnitus patients after repetitive transcranial magnetic stimulation.World journal of clinical cases · 2019Article
- Mechanisms of Transcranial Magnetic Stimulation Treating on Post-stroke Depression.Frontiers in human neuroscience · 2018Review
- Short-term effects of repetitive transcranial magnetic stimulation on sleep bruxism - a pilot study.International journal of oral science · 2016Article
- Factor Analysis of Low-Frequency Repetitive Transcranial Magnetic Stimulation to the Temporoparietal Junction for Tinnitus.Neural plasticity · 2016Article
- A systematic review of non-motor rTMS induced motor cortex plasticity.Frontiers in human neuroscience · 2015Review
- Post-stroke fatigue: a deficit in corticomotor excitability?Brain : a journal of neurology · 2015Article
Corrections and comments
- Erratum issuedKim, Hee Jin [corrected to Kim, Hee-Jin]
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeRepetitive transcranial magnetic stimulation (rTMS) has potential as a noninvasive neuromodulation treatment method for various neuropsychiatric disorders, and repeated sessions of rTMS are more likely to enhance the therapeutic efficacy. This study investigated neurophysiologic and spatiodynamic changes induced by repeated 1-Hz rTMS of the temporal cortex using transcranial magnetic stimulation (TMS) indices and fluorodeoxyglucose positron emission tomography (FDG-PET).
methodsTwenty-seven healthy subjects underwent daily 1-Hz active or sham rTMS of the right temporal cortex for 5 consecutive days. TMS indices of motor cortical excitability were measured in both hemispheres daily before and after each rTMS session, and 2 weeks after the last stimulation. FDG-PET was performed at baseline and after the 5 days of rTMS sessions.
resultsAll subjects tolerated all of the sessions well, with only three of them (11.1%) reporting mild transient side effects (i.e., headache, tinnitus, or local irritation). One-Hz rTMS decreased motor evoked potential amplitudes and delayed cortical silent periods in the stimulated hemisphere. Statistical parametric mapping of FDG-PET data revealed a focal reduction of glucose metabolism in the stimulated temporal area and an increase in the bilateral precentral, ipsilateral superior and middle frontal, prefrontal and cingulate gyri.
conclusionsRepeated rTMS sessions for 5 consecutive days were tolerated in all subjects, with only occasional minor side effects. Focal 1-Hz rTMS of the temporal cortex induces cortico-cortical modulation with widespread functional changes in brain neural networks via long-range neural connections.
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