ArticleFrontiers in physiology2013
Neurocognitive impairment in childhood chronic fatigue syndrome.
Article in Frontiers in physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Altered Effective Connectivity of Resting-State Networks by Tai Chi Chuan in Chronic Fatigue Syndrome Patients: A Multivariate Granger Causality Study.Frontiers in neurology · 2022Article
- Article
- Pediatric chronic fatigue syndrome: current perspectives.Pediatric health, medicine and therapeutics · 2017Review
- Low putamen activity associated with poor reward sensitivity in childhood chronic fatigue syndrome.NeuroImage. Clinical · 2016Article
- Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome.NeuroImage. Clinical · 2015Article
- Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life.Medical gas researchArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurocognitive impairment is a feature of childhood chronic fatigue syndrome (CCFS). Several studies have demonstrated reduced attention control in CCFS patients in switching and divided attention tasks. In students, the extent of deterioration in task performance depends on the level of fatigue. Poor performance in switching and divided attention is common in both fatigued students and CCFS patients. Additionally, attentional functions show dramatic development from childhood to adolescence, suggesting that abnormal development of switching and divided attention may be induced by chronic fatigue. The brain structures associated with attentional control are situated in the frontal and parietal cortices, which are the last to mature, suggesting that severe fatigue in CCFS patients and students may inhibit normal structural and functional development in these regions. A combination of treatment with cognitive behavioral therapy and antidepressant medication is effective to improve attentional control processing in CCFS patients. Studies identifying the features of neurocognitive impairment in CCFS have improved our current understanding of the neurophysiological mechanisms of CCFS.
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Registered trials
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