Evidence map›Paper›PMID 23626529›Full record

ArticleFrontiers in human neuroscience2013

Regional personalized electrodes to select transcranial current stimulation target.

Franca Tecchio, A Cancelli, C Cottone, L Tomasevic, B Devigus, G Zito, Matilde Ercolani, F Carducci

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
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  8. A New, High-Efficacy, Noninvasive Transcranial Electric Stimulation Tuned to Local Neurodynamics.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018
    Article
  9. Article
  10. Article
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  13. A technical guide to tDCS, and related non-invasive brain stimulation tools.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2016
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Franca TecchioLaboratory of Electrophysiology for Translational neuroScience (LET'S) - ISTC - CNR, Department of Neuroscience, Fatebenefratelli Hospital Rome, Italy ; Department of Neuroimaging, IRCCS San Raffaele Pisana Rome, Italy.
A Cancelli
C Cottone
L Tomasevic
B Devigus
G Zito
Matilde Ercolani
F Carducci
Consorzio Roma Ricerche · ITNational Research Council · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationalePersonalizing transcranial stimulations promises to enhance beneficial effects for individual patients.

objectiveTo stimulate specific cortical regions by developing a procedure to bend and position custom shaped electrodes; to probe the effects on cortical excitability produced when the properly customized electrode is targeting different cortical areas.

methodAn ad hoc neuronavigation procedure was developed to accurately shape and place the personalized electrodes on the basis of individual brain magnetic resonance images (MRI) on bilateral primary motor (M1) and somatosensory (S1) cortices. The transcranial alternating current stimulation (tACS) protocol published by Feurra et al. (2011b) was used to test the effects on cortical excitability of the personalized electrode when targeting S1 or M1.

resultsNeuronal excitability as evaluated by tACS was different when targeting M1 or S1, with the General Estimating Equation model indicating a clear tCS Effect (p < 0.001), and post hoc comparisons showing solely M1 20 Hz tACS to reduce M1 excitability with respect to baseline and other tACS conditions.

conclusionsThe present work indicates that specific cortical regions can be targeted by tCS properly shaping and positioning the stimulating electrode. SIGNIFICANCE: Through multimodal brain investigations continuous efforts in understanding the neuronal changes related to specific neurological or psychiatric diseases become more relevant as our ability to build the compensating interventions improves. An important step forward on this path is the ability to target the specific cortical area of interest, as shown in the present pilot work.

Indexed as

customized electrodesmotor cortexneuronavigationpersonalized stimulation targetsomatosensory cortextranscranial current stimulation

Identifiers

PMID23626529
PMCPMC3631708
OpenAlexW2000207192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.