Evidence map›Paper›PMID 23626400›Full record

ArticleColloid and polymer science2013

Novel pentablock copolymer (PLA-PCL-PEG-PCL-PLA) based nanoparticles for controlled drug delivery: Effect of copolymer compositions on the crystallinity of copolymers and in vitro drug release profile from nanoparticles.

Viral Tamboli, Gyan P Mishra, Ashim K Mitra

Abstract read
In one paragraph

Article in Colloid and polymer science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  10. The role of EPThe British journal of ophthalmology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Viral TamboliDivision of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, MO 64108-2718, USA.
Gyan P Mishra
Ashim K Mitra

Funding

Ocular Disposition of Antimicrobial AgentsR01EY009171 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI MITRA, ASHIM K. · 1992 to 2010
$3.0M
Transscleral Transport & Polymeric Delivery of Antibody & Steroids for Macular EdR01EY010659 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI MITRA, ASHIM K. · 1996 to 2010
$2.5M
NEI NIH HHS R01 EY009171NEI NIH HHS R01 EY010659
6 · The paper itself

Abstract

The purpose of this investigation was to design novel pentablock copolymers (polylatide-polycaprolactone-polyethylene glycol- polycaprolactone-polylatide) (PLA-PCL-PEG-PCL-PLA) to prepare nanoparticle formulations which provide continuous delivery of steroids over a longer duration with minimal burst effect. Another purpose was to evaluate the effect of poly (L-lactide) (PLLA) or poly (D, L-lactide) (PDLLA) incorporation on crystallinity of pentablock copolymers and

Indexed as

Block copolymersCorticosteroidsDrug deliveryNanotechnology

Identifiers

PMID23626400
PMCPMC3633208

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.