ArticleMethods in molecular biology (Clifton, N.J.)2013
Informatics of protein and posttranslational modification detection via shotgun proteomics.
Article in Methods in molecular biology (Clifton, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Article
- Bronchoalveolar lavage proteomics in exacerbation of bronchiectasis.BMC pulmonary medicine · 2025Article
- The role of multi-omics in biomarker discovery, diagnosis, prognosis, and therapeutic monitoring of tissue repair and regeneration processes.Journal of orthopaedic translation · 2025Review
- Harnessing Pharmacomultiomics for Precision Medicine in Diabetes: A Comprehensive Review.Biomedicines · 2025Review
- Implementation of multiomic mass spectrometry approaches for the evaluation of human health following environmental exposure.Molecular omics · 2024Review
- Proteomics and Its Current Application in Biomedical Area: Concise Review.TheScientificWorldJournal · 2024Review
- Urinary Peptidomics and Pulse Wave Velocity: The African-PREDICT Study.Journal of proteome research · 2023Article
- Precision diagnostics in children.Cambridge prisms. Precision medicine · 2023Review
- Conventional and Omics Approaches for Understanding the Abiotic Stress Response in Cereal Crops-An Updated Overview.Plants (Basel, Switzerland) · 2022Review
- Proteomic and Genomic Studies of Micronutrient Deficiency and Toxicity in Plants.Plants (Basel, Switzerland) · 2022Review
- Wheat Proteomics for Abiotic Stress Tolerance and Root System Architecture: Current Status and Future Prospects.Proteomes · 2022Review
- Proteomics: Concepts and applications in human medicine.World journal of biological chemistry · 2021Review
- A Fluorogenic Assay: Analysis of Chemical Modification of Lysine and Arginine to Control Proteolytic Activity of Trypsin.Molecules (Basel, Switzerland) · 2021Article
- Proteomic Analysis of Proteins Responsive to Drought and Low Temperature Stress in a Hard Red Spring Wheat Cultivar.Molecules (Basel, Switzerland) · 2020Article
- Pollen proteomics: from stress physiology to developmental priming.Plant reproduction · 2016Review
- Comprehensive Characterization of Glycosylation and Hydroxylation of Basement Membrane Collagen IV by High-Resolution Mass Spectrometry.Journal of proteome research · 2016Article
- Global, in situ, site-specific analysis of protein S-sulfenylation.Nature protocols · 2015Article
- Quantitative chemoproteomics for site-specific analysis of protein alkylation by 4-hydroxy-2-nonenal in cells.Analytical chemistry · 2015Article
- Advances in plant proteomics toward improvement of crop productivity and stress resistancex.Frontiers in plant science · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Frequently, proteomic LC-MS/MS data may contain sets of modifications that evade identification during standard database search. For many laboratories, the standard technique to seek posttranslational modifications (PTMs) adds a short list of specified mass shifts to database search configuration. This technique provides information for only the specified PTMs, takes substantial time to run, and drives false discoveries upward through an exponential expansion of search space. This protocol describes a more structured approach to blind PTM discovery through reducing protein lists, targeting attention to a data-driven list of mass shifts, and seeking the resulting short list of modifications through targeted search.
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Registered trials
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